Ohio

Gallium Trojan horse strategy defeats drug-resistant bacteria
Submitted by WebElements on 18 March 2007 - 7:49am.An article in the Journal of Clinical Investigation outlines how a new antimicrobial approach kills bacteria in laboratory experiments and eliminate life-threatening infections in mice by interfering with a key bacterial nutrient. Iron is critical for the growth of bacteria and for their ability to form biofilms, slime-encased colonies of microbes that cause many chronic infections. "Gallium acts as a Trojan horse to iron-seeking bacteria," said Pradeep Singh (senior author). "Because gallium looks like iron, invading bacteria are tricked, in a way, into taking it up.
