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P7C3 and an unbiased approach to drug discovery for neurodegenerative diseases

Chem. Soc. Rev. - 3 hours 56 min ago

Chem. Soc. Rev., 2014, 43,6716-6726
DOI: 10.1039/C3CS60448A, Review ArticleAndrew A. Pieper, Steven L. McKnight, Joseph M. Ready
The P7C3 compounds emerged from an in vivo screen and were found to protect neurons in models of neurodegenerative disease.
The content of this RSS Feed (c) The Royal Society of Chemistry

Differences between amyloid-[small beta] aggregation in solution and on the membrane: insights into elucidation of the mechanistic details of Alzheimer's disease

Chem. Soc. Rev. - 3 hours 56 min ago

Chem. Soc. Rev., 2014, 43,6692-6700
DOI: 10.1039/C3CS60431D, Tutorial ReviewSamuel A. Kotler, Patrick Walsh, Jeffrey R. Brender, Ayyalusamy Ramamoorthy
The association of the amyloid-[small beta] (A[small beta]) peptide with cellular membranes is hypothesized to be the underlying phenomenon of neurotoxicity in Alzheimer's disease.
The content of this RSS Feed (c) The Royal Society of Chemistry

Diketopyrrolopyrrole: brilliant red pigment dye-based fluorescent probes and their applications

Chem. Soc. Rev. - 3 hours 56 min ago

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00248B, Tutorial ReviewMatinder Kaur, Dong Hoon Choi
The review summarizes the recent development of various DPP-based fluorescent probes for tracing biologically and environmentally important species.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Correction: The physical properties of supramolecular peptide assemblies: from building block association to technological applications

Chem. Soc. Rev. - 3 hours 56 min ago
Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS90080D, CorrectionLihi Adler-Abramovich, Ehud Gazit
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The content of this RSS Feed (c) The Royal Society of Chemistry

Transition-metal-free C-C bond forming reactions of aryl, alkenyl and alkynylboronic acids and their derivatives

Chem. Soc. Rev. - 3 hours 56 min ago

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00195H, Tutorial ReviewS. Roscales, A. G. Csaky
Transition-metal-free C-C bond forming reactions of boronic acids are new emerging tools in organic synthesis which complement metal-based procedures.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Strategies for improving the performance and stability of Ni-based catalysts for reforming reactions

Chem. Soc. Rev. - 3 hours 56 min ago

Chem. Soc. Rev., 2015, Advance Article
DOI: 10.1039/C4CS00223G, Tutorial ReviewShuirong Li, Jinlong Gong
This review describes recent progress in the design and synthesis of nickel catalysts with anti-coke and -sintering properties for reforming processes.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Upconverting nanoparticles: assessing the toxicity

Chem. Soc. Rev. - 3 hours 56 min ago

Chem. Soc. Rev., 2015, Advance Article
DOI: 10.1039/C4CS00177J, Review ArticleAnna Gnach, Tomasz Lipinski, Artur Bednarkiewicz, Jacek Rybka, John A. Capobianco
Based on a survey of existing studies, low nanotoxicity of lanthanide doped upconverting nanoparticles holds promise for their safety and suitability for biomedical detection and imaging.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Surface modification and characterization of photon-upconverting nanoparticles for bioanalytical applications

Chem. Soc. Rev. - 3 hours 56 min ago

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00186A, Review ArticleAndreas Sedlmeier, Hans H. Gorris
A well-defined surface architecture is essential to generate water-dispersible UCNPs that are long-term stable and enable a wealth of bioanalytical applications.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Stability enhancement of fluorophores for lighting up practical application in bioimaging

Chem. Soc. Rev. - 3 hours 56 min ago

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00152D, HighlightXumeng Wu, Weihong Zhu
In this Highlight, we emphasize some representative strategies including nanoparticle-encapsulating dyes, dye-doped nanoparticles and molecular engineering for stabilizing fluorophores.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Bioapplications of hyperbranched polymers

Chem. Soc. Rev. - 3 hours 56 min ago

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00229F, Review ArticleDali Wang, Tianyu Zhao, Xinyuan Zhu, Deyue Yan, Wenxin Wang
The recent research progress in biological and biomedical applications of hyperbranched polymers has been summarized in this review.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Functional hyperbranched polymers with advanced optical, electrical and magnetic properties

Chem. Soc. Rev. - 3 hours 56 min ago

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00224E, Review ArticleWenbo Wu, Runli Tang, Qianqian Li, Zhen Li
This review summarizes the recent progress in functional HBPs and their application in optics, electronics and magnetics, including light-emitting devices, aggregation-induced emission materials, nonlinear optical materials, chemosensors, solar cells, magnetic materials, etc., and provides outlooks for further exploration in the field.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Metal-catalyzed activation of ethers via C-O bond cleavage: a new strategy for molecular diversity

Chem. Soc. Rev. - 3 hours 56 min ago

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00206G, Review ArticleJosep Cornella, Cayetana Zarate, Ruben Martin
This review highlights the prospective impact of simple ethers as aryl halide surrogates in the cross-coupling arena via C-O bond-activation.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Near-infrared spectroscopy and hyperspectral imaging: non-destructive analysis of biological materials

Chem. Soc. Rev. - 3 hours 56 min ago

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00062E, Tutorial ReviewMarena Manley
Principles, interpretation and applications of near-infrared (NIR) spectroscopy and NIR hyperspectral imaging are reviewed.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Molecular medicine and neurodegenerative diseases

Chem. Soc. Rev. - 3 hours 56 min ago

Chem. Soc. Rev., 2014, 43,6668-6671
DOI: 10.1039/C4CS90065K, EditorialChristopher J. Chang, Benjamin F. Cravatt, Douglas S. Johnson, Mi Hee Lim
Guest editors Christopher J. Chang, Benjamin F. Cravatt, Douglas S. Johnson and Mi Hee Lim introduce the Molecular medicine and neurodegenerative diseases themed issue of Chemical Society Reviews.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biological metals and metal-targeting compounds in major neurodegenerative diseases

Chem. Soc. Rev. - 3 hours 56 min ago

Chem. Soc. Rev., 2014, 43,6727-6749
DOI: 10.1039/C4CS00138A, Review ArticleKevin J. Barnham, Ashley I. Bush
Metals are functionally essential, but redistribute in neurodegenerative disease where they induce protein aggregates, catalyze radical formation, and lose bioavailability.
The content of this RSS Feed (c) The Royal Society of Chemistry

O-GlcNAc and neurodegeneration: biochemical mechanisms and potential roles in Alzheimer's disease and beyond

Chem. Soc. Rev. - 3 hours 56 min ago

Chem. Soc. Rev., 2014, 43,6839-6858
DOI: 10.1039/C4CS00038B, Review ArticleScott A. Yuzwa, David J. Vocadlo
Increasing levels of glucose responsive O-GlcNAcylation of proteins in Alzheimer disease mouse models decreases the toxicity of tau and A[small beta].
The content of this RSS Feed (c) The Royal Society of Chemistry

Ideal Gas Law Simulation

Merlot chemistry - 19 September, 2014 - 23:17
An effective tool to help students learn about all aspects of the ideal gas law. One of the best web gas law simulations.
Categories: Education

Assessing Blood Pressure

Merlot chemistry - 19 September, 2014 - 23:17
This learning module presents the proper technique and common errors associated with assessment of blood pressure. The information is targeted at new learners in the clinical and health sciences and can serve as a review for current practitioners. The program includes audio of blood pressure sounds, interactive simulations, and self-assessment tools.
Categories: Education

DNA from the Beginning

Merlot chemistry - 19 September, 2014 - 23:17
DNA from the Beginning is an animated tutorial on DNA, genes and heredity. The science behind each concept is explained using animations related to DNA topics, an image gallery, video interviews, problems, biographies, and links related to DNA. There are three sections, Classical Genetics, Molecules of Genetics and Organization of Genetic Material. Key features are the clear explanations of classical experiments and the excellent photographs of researchers and their labs.For information and credits on the development of DNA from the Beginning, go to http://www.dnaftb.org/dnaftb/credits.html
Categories: Education

VR Molecules

Merlot chemistry - 19 September, 2014 - 23:17
VR Molecules presents dynamically and interactively the vibration and rotation modes for 24 molecules (out of a more extensive list) containing up to twelve atoms. It allows the user to create and save on his or her hard disk documents containing, much in the same way as Power Point presentations, up to 10 "pages״, each featuring one or two molecules with specific parameters (viewpoint, active modes, etc.). These presentations can be made available through the Internet, with optional sound and text explanations associated with each page.The latest, augmented version of VR Molecules, called VR Molecules Pro 1.1, is available online as well as in a stand-alone version (Mac and Windows). To view a video of the award winning author, go to View VR Molecules - Chemistry Award Winner 2007 video VR Molécules est un logiciel de simulation (en ligne et en mode local) permettant de visualiser et d'explorer les modes de vibration et de rotation des molécules (24 molécules sont disponibles). Il peut tout aussi bien être utilisé par le professeur pour préparer des démonstrations en classe, intégrer des animations (interactives ou non) dans ses documents HTML, que par les étudiants pour revoir les démonstrations présentées en classe et explorer par eux-mêmes la vibration et la rotation des molécules.La plus récente version (1.12) de VR Molécules, est accessible en deux versions : en ligne et en mode local (à télécharger, pour Mac et Windows).
Categories: Education

WebElements: the periodic table on the WWW [http://www.webelements.com/]

Copyright 1993-2011 Mark Winter [The University of Sheffield and WebElements Ltd, UK]. All rights reserved.