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BACE1 ([small beta]-secretase) inhibitors for the treatment of Alzheimer's disease

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C3CS60460H, Review ArticleArun K. Ghosh, Heather L. Osswald
The review highlights the progress in the design and development of BACE1 ([small beta]-secretase) inhibitors for the treatment of Alzheimer's disease.
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Structure of organic solids at low temperature and high pressure

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00046C, Tutorial ReviewRachael Lee, Judith A. K. Howard, Michael R. Probert, Jonathan W. Steed
This tutorial review summarises the current state of the art in low temperature and high pressure crystallography of molecular organic and coordination compounds.
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Garnet-type solid-state fast Li ion conductors for Li batteries: critical review

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00020J, Review ArticleVenkataraman Thangadurai, Sumaletha Narayanan, Dana Pinzaru
This review covers the research developments in the last decade on the most favored fast Li ion conducting garnet-type metal oxides for all-solid-state Li ion batteries.
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Recent developments of thiacalixarene based molecular motifs

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00068D, Review ArticleRajesh Kumar, Yeon Ok Lee, Vandana Bhalla, Manoj Kumar, Jong Seung Kim
This review article summarizes recent developments in the derivatization methods of thiacalixarenes and their utilization in various applications.
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About supramolecular systems for dynamically probing cells

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00034J, Review ArticleJenny Brinkmann, Emanuela Cavatorta, Shrikrishnan Sankaran, Bettina Schmidt, Jasper van Weerd, Pascal Jonkheijm
Rendering molecular systems bioactive and dynamic makes them powerful tools for probing cell function.
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Progress in the synthesis and exploitation of catenanes since the Millennium

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00029C, Review ArticleNicholas H. Evans, Paul D. Beer
Key developments including the utilization of new metal cation and anion templates, dynamic combinatorial chemistry, molecular machines and the incorporation of catenanes onto surfaces and into metal organic frameworks are reviewed.
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Metal-metalloporphyrin frameworks: a resurging class of functional materials

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00001C, Review ArticleWen-Yang Gao, Matthew Chrzanowski, Shengqian Ma
This review presents comprehensively recent progress in metal-metalloporphyrin frameworks with an emphasis on versatile functionalities.
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Chemical approaches to therapeutically target the metabolism and signaling of the endocannabinoid 2-AG and eicosanoids

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00047A, Review ArticleRebecca A. Kohnz, Daniel K. Nomura
This review describes the development of inhibitors for endocannabinoid metabolism and their potential therapeutic benefit.
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PET/SPECT imaging agents for neurodegenerative diseases

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C3CS60430F, Tutorial ReviewLin Zhu, Karl Ploessl, Hank F. Kung
Amyvid/PET imaging of a living brain detects [small beta]-amyloid plaque deposition, a risk factor for developing Alzheimer's disease.
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Recent advances in the synthesis of pyrroles by multicomponent reactions

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C3CS60015G, Review ArticleVeronica Estevez, Mercedes Villacampa, J. Carlos Menendez
Efficient and environmentally attractive access to pyrroles can be gained by use of multicomponent reactions.
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Recent advances in porous polyoxometalate-based metal-organic framework materials

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C3CS60404G, Review ArticleDong-Ying Du, Jun-Sheng Qin, Shun-Li Li, Zhong-Min Su, Ya-Qian Lan
POM-based MOF materials, which combine the advantages of both POMs and MOFs, have received increasing attention. In this review, we present the recent developments in porous POM-based MOF materials for the first time, including their classification, synthesis strategies and applications, especially in the field of catalysis.
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Chemical applications carried out by local pair natural orbital based coupled-cluster methods

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00050A, Review ArticleManuel Sparta, Frank Neese
Local pair natural orbital coupled-cluster methods are suitable for accurate assessment of the energies of large molecular and supramolecular systems.
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Laboratory spectroscopy of astrophysically relevant carbon species

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00049H, Review ArticleLindsay N. Zack, John P. Maier
Laboratory spectroscopic methods developed to measure the electronic spectra of astrophysically relevant carbon containing molecules, including radicals and ions, are discussed.
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Progress in allene chemistry

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, 43,2886-2887
DOI: 10.1039/C4CS90020K, EditorialBenito Alcaide, Pedro Almendros
Guest editors Benito Alcaide and Pedro Almendros introduce the Progress in allene chemistry themed issue of Chemical Society Reviews.
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Mechanistic insights into the gold chemistry of allenes

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, 43,2941-2955
DOI: 10.1039/C3CS60441A, Tutorial ReviewWeibo Yang, A. Stephen K. Hashmi
In the last few years numerous new gold-catalysed reactions of allenes have been developed. The current mechanistic knowledge about different versatile reaction types like cycloadditions, hydroarylations, hydroalkoxylations and additions of carbonyl derivatives is based on experimental evidence and computational studies.
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Synthesis and properties of long [n]cumulenes (n [greater-than-or-equal] 5)

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, 43,3184-3203
DOI: 10.1039/C4CS00022F, Review ArticleJohanna A. Januszewski, Rik R. Tykwinski
This review highlights the synthesis and reactivity of longer [n]cumulenes (n [greater-than-or-equal] 5) and summarizes their electronic and structural properties.
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Metal complexes designed to bind to amyloid-[small beta] for the diagnosis and treatment of Alzheimer's disease

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00026A, Review ArticleDavid J. Hayne, SinChun Lim, Paul S. Donnelly
The use radioactive copper and technetium complexes as amyloid imaging agents, the use of luminescent metal complexes as non-conventional probes of amyloid formation and the potential of metal complexes to be inhibitors of amyloid toxicity are discussed.
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Zeolites as catalysts in oil refining

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C3CS60394F, Tutorial ReviewAna Primo, Hermenegildo Garcia
This tutorial review describes the general properties of zeolites and their prevalent role as heterogeneous catalysts in oil refining.
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Protein film photoelectrochemistry of the water oxidation enzyme photosystem II

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, Advance Article
DOI: 10.1039/C4CS00031E, Tutorial ReviewMasaru Kato, Jenny Z. Zhang, Nicholas Paul, Erwin Reisner
This review describes key functions of the water oxidation enzyme photosystem II, protein film photoelectrochemistry of photosystem II and bio-inspired photoelectrochemical water oxidation systems.
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Silver and platinum-catalysed addition of O-H and N-H bonds to allenes

Chem. Soc. Rev. - 23 April, 2014 - 12:54

Chem. Soc. Rev., 2014, 43,3164-3183
DOI: 10.1039/C3CS60408J, Review ArticleMaria Paz Munoz
Silver and platinum-catalysed reactions of allenes with oxygen and nitrogen nucleophiles are presented in this review as powerful tools for the synthesis of functionalized molecules containing heteroatoms.
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