Feed aggregator

Total Synthesis of Macrodiolide Ionophores Aplasmomycin and Boromycin via Double Ring Contraction

Org. and Biomol. Chem. - 31 July, 2014 - 11:54
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB01017E, PaperJames D White, Mitchell A Avery, Brian Gray, Alan Whittle, Prakash Dhingra, Shen-chun Kuo, Satish C Choudhry, Myung-chol Kang, Thalatani R. Vedananda
The half structure of the symmetrical macrodiolide aplasmomycin A was synthesized by alkylation of a C3-C10 -sulfonyl ketone subunit, prepared from (R)-pulegone and protected as a C3 ortholactone with (2R,3R)-butanediol,...
The content of this RSS Feed (c) The Royal Society of Chemistry

Developing principles for predicting ionic liquid effects on reaction outcome. A demonstration using a simple condensation reaction

Org. and Biomol. Chem. - 31 July, 2014 - 11:54
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB01070A, PaperSinead T Keaveney, Karin S Schaffarczyk McHale, Ronald S Haines, Jason B Harper
The effects of a series of ionic liquids, with systematic variations in the cation, on the condensation of an alkyl amine with an aromatic aldehyde were investigated, and the outcomes...
The content of this RSS Feed (c) The Royal Society of Chemistry

Indole synthesis from N-allenyl-2-iodoanilines under mild conditions mediated by samarium(II) diiodide

Org. and Biomol. Chem. - 31 July, 2014 - 11:54

Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01164C, CommunicationHiroki Iwasaki, Kenji Suzuki, Mitsunari Yamane, Shohei Yoshida, Naoto Kojima, Minoru Ozeki, Masayuki Yamashita
A novel method for indole skeleton synthesis under mild conditions mediated by samarium(II) diiodide has been developed.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

A convenient tandem one-pot synthesis of donor-acceptor-type triphenylene 2,3-dicarboxylic esters from diarylacetylene

Org. and Biomol. Chem. - 31 July, 2014 - 11:54
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB01503G, Communicationchun Feng, Xian-Li Tian, Jing Zhou, Shi-Kai Xiang, Wen-Hao Yu, Bi-Qin Wang, Ping Hu, Carl Redshaw, Keqing Zhao
A tandem one-pot method for the direct synthesis of polysubstituted triphenylene 2,3-dicarboxylic esters with different substitution patterns has been developed through enyne metathesis of diarylacetylene, followed by Diels-Alder, aromatization and...
The content of this RSS Feed (c) The Royal Society of Chemistry

68Ga based Probe for Alzheimer's Disease: Synthesis and Preclinical Evaluation of Homodimeric Chalcone in [small beta]-Amyloid Imaging

Org. and Biomol. Chem. - 31 July, 2014 - 11:54
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB00941J, PaperKanchan Chauhan, Anupama Datta, Anupriya Adhikari, Krishna Chuttani, Ajai kumar Singh, Anil K Mishra
In an attempt to explore PET radioisotope, 68Ga in the diagnosis of Alzheimer's disease, a metal based homodimeric ligand exhibiting high affinity towards A[small beta] aggregates was designed by conjugating two...
The content of this RSS Feed (c) The Royal Society of Chemistry

Short asymmetric synthesis of phenanthroindolizidines through chiral homoallylic sulfinamines

Org. and Biomol. Chem. - 31 July, 2014 - 11:54

Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01133C, PaperCintia Anton-Torrecillas, Jose C. Gonzalez-Gomez
An expeditious synthesis of enantioenriched phenanthroindolizidines has been achieved using tert-butylsulfinamide as a chiral inductor and without any other protecting group.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Light-driven artificial enzymes for selective oxidation of guanosine triphosphate using water-soluble POSS network polymers

Org. and Biomol. Chem. - 31 July, 2014 - 11:54

Org. Biomol. Chem., 2014, 12,6500-6506
DOI: 10.1039/C4OB01115E, PaperJong-Hwan Jeon, Kazuo Tanaka, Yoshiki Chujo
The light-driven artificial enzymes were constructed to realize unnatural reactions concerning biomolecules. The guanosine triphosphate-selective oxidation was accomplished using the network polymers in which the molecular recognition via hydrogen bonds can be enhanced.
The content of this RSS Feed (c) The Royal Society of Chemistry

Novel EDTA-ligands containing an integral perylene bisimide (PBI) core as an optical reporter unit

Org. and Biomol. Chem. - 31 July, 2014 - 11:54

Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01007H, PaperMario Marcia, Prabhpreet Singh, Frank Hauke, Michele Maggini, Andreas Hirsch
The synthesis, characterization and metal complexation of a new class of perylene bisimides (PBIs) as an integral part of ethylenediaminetetraacetic acid (EDTA) are reported.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

TBAI-catalyzed oxidative synthesis of benzamides from acetophenones and carbinols

Org. and Biomol. Chem. - 31 July, 2014 - 11:54

Org. Biomol. Chem., 2014, 12,6359-6362
DOI: 10.1039/C4OB01203H, CommunicationMuhammad Sharif, Jianbin Chen, Peter Langer, Matthias Beller, Xiao-Feng Wu
An interesting and convenient procedure for the oxidative transformation of acetophenones and carbinols to primary benzamides has been developed.
The content of this RSS Feed (c) The Royal Society of Chemistry

Catalytic control over the formation of supramolecular materials

Org. and Biomol. Chem. - 31 July, 2014 - 11:54

Org. Biomol. Chem., 2014, 12,6292-6296
DOI: 10.1039/C4OB01108B, PerspectiveRienk Eelkema, Jan H. van Esch
Catalytic formation of self-assembling building blocks provides control over the morphology, mechanical properties and spatial distribution of soft supramolecular materials.
The content of this RSS Feed (c) The Royal Society of Chemistry

Access to novel functionalized trifluoromethyl [small beta]-lactams by ring expansion of aziridines

Org. and Biomol. Chem. - 31 July, 2014 - 11:54

Org. Biomol. Chem., 2014, 12,6345-6348
DOI: 10.1039/C4OB01262C, CommunicationS. Decamps, L. Sevaille, S. Ongeri, B. Crousse
A wide variety of CF3-[small beta]-lactams functionalized at position C-3 were obtained stereoselectively by ring expansion of aziridines.
The content of this RSS Feed (c) The Royal Society of Chemistry

Copper-catalyzed arylsulfonylation of N-arylsulfonyl-acrylamides with arylsulfonohydrazides: synthesis of sulfonated oxindoles

Org. and Biomol. Chem. - 31 July, 2014 - 11:54

Org. Biomol. Chem., 2014, 12,6349-6353
DOI: 10.1039/C4OB01231C, CommunicationQingshan Tian, Ping He, Chunxiang Kuang
A copper-catalyzed arylsulfonylation of N-arylsulfonyl-acrylamides with sulfonylhydrazides through a tandem radical process was developed.
The content of this RSS Feed (c) The Royal Society of Chemistry

Comparison of the substrate selectivity and biochemical properties of human and bacterial [gamma]-butyrobetaine hydroxylase

Org. and Biomol. Chem. - 31 July, 2014 - 11:54

Org. Biomol. Chem., 2014, 12,6354-6358
DOI: 10.1039/C4OB01167H, CommunicationAnna M. Rydzik, Ivanhoe K. H. Leung, Grazyna T. Kochan, Nikita D. Loik, Luc Henry, Michael A. McDonough, Timothy D. W. Claridge, Christopher J. Schofield
BBOX is a 2-oxoglutarate dependent oxygenase that can catalyse formation of vicinal diols and amino alcohols.
The content of this RSS Feed (c) The Royal Society of Chemistry

Total synthesis of the cyclic monoterpenoid pyrano[3,2-a]carbazole alkaloids derived from 2-hydroxy-6-methylcarbazole

Org. and Biomol. Chem. - 31 July, 2014 - 11:54

Org. Biomol. Chem., 2014, 12,6490-6499
DOI: 10.1039/C4OB01151A, PaperCemena Gassner, Ronny Hesse, Arndt W. Schmidt, Hans-Joachim Knolker
The synthesis of seven pyrano[3,2-a]carbazole alkaloids has been achieved using their putative biogenetic precursor 2-hydroxy-6-methylcarbazole as key intermediate.
The content of this RSS Feed (c) The Royal Society of Chemistry

Stereoselective one-pot synthesis of [small beta]-alkylsulfide enol esters. Base-triggered rearrangement under mild conditions

Org. and Biomol. Chem. - 31 July, 2014 - 11:54

Org. Biomol. Chem., 2014, 12,6516-6526
DOI: 10.1039/C4OB01011F, PaperAdrian A. Heredia, Silvia M. Soria-Castro, Lydia M. Bouchet, Gabriela Oksdath-Mansilla, Cecilia A. Barrionuevo, Daniel A. Caminos, Fabricio R. Bisogno, Juan E. Arguello, Alicia B. Penenory
(Z)-Vinyl sulfides are easily synthesised through a multicomponent reaction. An intramolecular S,O-acyl migration accounts for the observed stereoselectivity.
The content of this RSS Feed (c) The Royal Society of Chemistry

Synthesis of 3,3-disubstituted-2,3-dihydroazanaphthoquinones via simultaneous alkyne oxidation and nitrile hydration of ortho-alkynylarenenitriles

Org. and Biomol. Chem. - 31 July, 2014 - 11:54

Org. Biomol. Chem., 2014, 12,6440-6446
DOI: 10.1039/C4OB00852A, PaperKaruppusamy Sakthivel, Kannupal Srinivasan
Simultaneous activation of alkynes and nitriles in o-alkynylarenenitriles in the presence of Pd(OAc)2/H2O/(+/-)-CSA afforded 3,3-disubstituted-2,3-dihydroazanaphthoquinones in moderate to excellent yields.
The content of this RSS Feed (c) The Royal Society of Chemistry

C-H arylation of azaheterocycles: a direct ligand-free and Cu-catalyzed approach using diaryliodonium salts

Org. and Biomol. Chem. - 31 July, 2014 - 11:54

Org. Biomol. Chem., 2014, 12,6340-6344
DOI: 10.1039/C4OB01061B, CommunicationDalip Kumar, Meenakshi Pilania, V. Arun, Savita Pooniya
An efficient and high yielding Cu-catalyzed direct C-H arylation of oxadiazoles, thiadiazoles, benzoxazoles and benzothiazoles has been achieved by employing easily accessible diaryliodonium salts.
The content of this RSS Feed (c) The Royal Society of Chemistry

P,N,N-Pincer nickel-catalyzed cross-coupling of aryl fluorides and chlorides

Org. and Biomol. Chem. - 31 July, 2014 - 11:54

Org. Biomol. Chem., 2014, 12,6414-6424
DOI: 10.1039/C4OB01041H, PaperDan Wu, Zhong-Xia Wang
P,N,N-Pincer nickel was demonstrated to effectively catalyze cross-coupling of aryl fluorides and chlorides with aryl magnesium or zinc reagents.
The content of this RSS Feed (c) The Royal Society of Chemistry

A "click" chemistry constructed affinity system for 2-oxoglutaric acid receptors and binding proteins

Org. and Biomol. Chem. - 31 July, 2014 - 11:54

Org. Biomol. Chem., 2014, 12,6470-6475
DOI: 10.1039/C4OB01005A, PaperYang Wang, Zeinab Assaf, Xinjun Liu, Fabio Ziarelli, Amel Latifi, Otmane Lamrabet, Gilles Quelever, Fanqi Qu, Cheng-Cai Zhang, Ling Peng
An ingenious and robust affinity resin to capture the 2-oxoglutaric acid binding proteins was constructed via "click" chemistry and validated using a known 2-OG receptor in cell lysate.
The content of this RSS Feed (c) The Royal Society of Chemistry

Facile access to amides and hydroxamic acids directly from nitroarenes

Org. and Biomol. Chem. - 31 July, 2014 - 11:54

Org. Biomol. Chem., 2014, 12,6465-6469
DOI: 10.1039/C4OB01155D, PaperShreyans K. Jain, K. A. Aravinda Kumar, Sandip B. Bharate, Ram A. Vishwakarma
Herein, we report a new method for synthesis of amides and hydroxamic acids directly from nitroarenes and aldehydes.
The content of this RSS Feed (c) The Royal Society of Chemistry

WebElements: the periodic table on the WWW [http://www.webelements.com/]

Copyright 1993-2011 Mark Winter [The University of Sheffield and WebElements Ltd, UK]. All rights reserved.