Obviously, a good old-fashioned circular slice of polyvinyl chloride, PVC, or just vinyl to audiophiles, is a disc, two sides, A and B, sometimes labelled A and A…but what if you want three sides? Is it possible to have a hyper-disk with an extra groovy surface? In reality, maybe not. In virtuality…
Life, Love and Lonicera: My triple A-side single featuring a Pseudo Gabriel pastiche “Push the Button”, my feverish asthmatic falsetto in the mock jazz of “Wild Honeysuckle” and the slow build and gospelesque break of “Burning Out” featuring original lyrics by my good friend and singing partner JH Livingstone.
Original source: A triple A-side meta single by David Bradley.
The Geordie geography of TV’s George Gently (which has been on for years) is quite amazing…I watch it because it’s filmed in the land of my birth. But, Scene 1 might be in a children’s home in Teesside (which they spell Teeside), next scene is Gently, who’s based in Durham, which is on the Wear, nipping down to said kids’ home with sidekick mod copper John, then they’re back in time for Gently to quickly get to South Shields only it isn’t South Shields (on the Tyne), which they call “Shields”, it’s Seaton Sluice, which is back over the Tyne and further North. Then they’re driving into somewhere they said was Whitley Bay, but there are grassy sand dunes and it’s so obviously Druridge Bay (where they didn’t build a nuclear power station, I was at the punk protest gig in 1977!).
Next, they’re in Cullercoasts, where I grew up, but it’s not, it’s somewhere near Roker, and so on and so forth, until Gently, case solved is standing knee deep in his waders flyfishing on a wear (against fishing rules, I think) in the shadow of Durham Cathedral (his favourite building).
Somehow they span three counties, three rivers, and at least a hundred different attempts at an authentic Geordie accent and all the while not once mentioning The Toon, Mac’ems, or the name of the place they’re actually meant to be stationed in. Oh, and they never have scenes where they are driving for more than a few seconds, presumably for fear of framing modern street furniture, like that enormous CCTV pole outside the Spanish City in S02E03.
It is good though…I love the authenticity of the interiors, all that bevelled glass and kitsch ornaments…and it certainly beats Heartbeat. Next week, Sciencebase dissect’s Vera’s “Geordie accent” and her eternal penchant for the Rendezvous Cafe…
Original source: George’s Gentle Geordie Geography by David Bradley.
Having mentioned 100 million chemicals just now, be sheer chance, I noticed that “Push the Button” stacks up as my 100th original tune on SoundCloud. It’s part of the double A-side “single” – Life Love, and Lonicera, which includes my big time Pseudo Gabriel sledgehammer of a song, “Push the Button” and Wild Honeysuckle which features my feverish festival falsetto, songs of sexuality on steroids…but NOT NSFW ;-)
Original source: 100 songs by David Bradley.
One little bit of chemistry news that I always try to cover are the milestones as the Chemical Abstracts Service announces the next “round number” in its database of chemical structures. It was September 2007 when I mentioned their reaching 50 million structures, but I am fairly sure I wrote about their 10 millionth in newscientist back in the early 1990s…
This week, CAS announced the 100 millionth chemical substance in its registry in the service’s 50th anniversary. That is quite astounding, 100 million chemicals! On average a new substance registered every two and a half minutes since 1965, although three quarters of the entries were added only in the last decade.
The 100 millionth (entry references CAS RN 1786400-23-4) is a drug for acute myeloid leukaemia, developed by Coferon in Stony Brook, New York, USA.
Original source: 100 million chemicals by David Bradley.
A fascinating paper highlighted in F1000 Prime suggests that powdered tomato (the red-coloured lycopene in it, actually) has a protective effect on a liver diseased by alcohol. Specifically, “dietary tomato powder inhibits alcohol-induced hepatic injury by suppressing cytochrome p450 2E1 induction in rodent models.” So if you’re a boozed up critter it might help. What I am waiting with baited breath to see are the tabloid headlines when they get wind of this research:Bloody Mary cures ailing liver
That kind of thing…
This from the paper’s abstract:Chronic and excessive alcohol consumption leads to the development of alcoholic liver disease (ALD) and greatly increases the risk of liver cancer. Induction of the cytochrome p450 2E1 (CYP2E1) enzyme by chronic and excessive alcohol intake is known to play a role in the pathogenesis of ALD. High intake of tomatoes, rich in the carotenoid lycopene, is associated with a decreased risk of chronic disease.
Of course, the paper says nothing of the sort wrt the Bloody Mary, it just hints at a component of tomato powder having a putatively beneficial effect on liver enzymes in a laboratory animal. I gave it a tweet and Justin Brower aka Nature Poisons, a forensic toxicologist and organic chemist, offered up the idea of a powdered Bloody Mary made from “powdered alcohol” and powdered tomato, he called it “The Jane Doe Bloodstain”, to which I then offered the hashtag Dexter. Thus, was born the ultimate boozy liver scientist’s cocktail: A Dexter on the
Rocks. Watch out for the gory end of season finale…cheers!
CC “Bloody Mary” photo by https://www.flickr.com/photos/fstorr
Original source: Dexter on the Rocks by David Bradley.
There are countless sites for depositing and sharing one’s photos online. Mine are scattered across Flickr, 500px, Facebook, Google+, FineArt, and various others as well as on my Imaging Storm Photography website.
Below a hastily constructed test gallery of just a few of my many hundreds of photos.
Original source: Dave Bradley Photography by David Bradley.
Here’s a very quickfire summary of an excellent article by Sally Bloomfield of the London School of Hygiene & Tropical Medicine, published in The Conversation.
- Fewer childhood infections does not lead to more allergies
- Our modern “obsession” with cleanliness is not to blame for more people having allergies
- Being less hygienic will not reverse the allergy trend
- Synthetic chemicals are not to blame for allergies
On that latter issue about “synthetic” chemicals Bloomfield makes a very important point that the public should know:
Many people believe that ‘man-made’ chemicals are more likely to cause allergic reactions, leading to many synthetic substances in products being replaced by ‘atural alternatives’. However, the most common allergic reactions are to naturally occurring allergens, in foods such as eggs, milk and nuts, in common garden plants such as primroses and chrysanthemums, and things in the environment such as pollen, dust mites and pet dander. Some natural replacements for synthetic substances could actually increase the risk of allergic reactions.
Creative Commons photo by peapodlabs
Original source: Allergy myths debunked by David Bradley.
Is skipping breakfast bad for you? Back in the 1970s, there was a campaign that led with the line “go to work on an egg”, but that was just a promo for the egg marketing people, or was it? The so-called “health” and “lifestyle” magazines often splash with the idea that you must have a good breakfast as it “sets you up for the day” and helps avoid snacking during the rest of the day, controls sugar spikes, helps metabolism, all that kind of tosh.
About a year ago British tabloids got hold of a story claiming that brekkie isn’t the most important meal, it was a tiny trial and the news stories were dismantled by NHS Choices’ “Behind the headlines“. On several occasions prior to that there were news reports that regularly skipping breakfast leads to a greater risk of having a heart attack in men. And before that claims that missing breakfast when you’re a child can increase the risk of developing Type 2 diabetes later in life. And, then there was the question of the big breakfast and whether skipping breakfast leads to our seeking out fatty foods later in the day. Again media stories critiqued by the NHS (follow those links).
The NHS site has some recipes for people who feel they ought to have breakfast but cannot face the traditional breakfast fare first thing in the morning. WebMD reckons breakfast is important. As does Johns Hopkins in some advice for students. Similar fodder on the Mayo Clinic site. But for every dozen breaskfast recipes mentioned on the web, every 365 breakfast bars unwrapped, there seems to be at least one citation of some study or another that suggests skipping breakfast is not bad for you, may well do you good, or perhaps not, who knows, definitely maybe!
It would be nice if there were a simple answer. And, perhaps there is: eat when you’re hungry, get plenty of fresh air and exercise, drink enough water so that you don’t feel thirsty and avoid the real nasties: tobacco smoke, drunk drivers and (when you’re really ill) quacks such as homeopaths.
CC “Full English Breakfast” photo by homard
Original source: Skipping breakfast – good or bad? by David Bradley.
Moody freelance science journalist, David Bradley (aka sciencebase) famed for his depressing social media avatar and miserable lack of photogenicity, cracked the lens today when his daughter snapped a few photos of him pensively and pointlessly propped up against the headstock of his Fender Telecaster Guitar. In one of 27 headshots, Bradley is actually seen to be smiling at the camera. The photograph has now been quickly uploaded to the Gravatar servers, and used to replace his Twitter avatar and his Facebook profile photo before his mood changes. There were three seconds of absolute stunned silence across the whole of social media and in science laboratories the world over as a mark of respect. Frontpages have been held…
Original source: Science journalist smiles by David Bradley.
In case you didn’t know, I’m a science journalist by day, a photographer on my days off and a musician by night. Been fretting guitar strings since I was about 12 years old, but only in recent years have I performed live and written and recorded complete, original songs.
My music – originals and covers available on: iTunes, BandCamp, Spotify, Google Play, Youtube, ReverbNation, SoundCloud, Tradiio, Gumroad, Beat100, Spotify and other outlets including Pandora, Deezer, Rdio, Amazon mp3, Loudr, MixCloud.
Here’s a very short list of a few of musicians, bands and artists I admire: Athlete, The Beatles, bigMouth, Blur, David Bowie, Kate Bush, Crowded House, The Cure, John Denver, Doves, Editors, Elbow, Fred’s House, Peter Gabriel, The Kinks, Led Zeppelin, Manic Street Preachers, Van Morrison, Gerry Rafferty, R.E.M., Nile Rodgers, Rush, The Smiths, James Taylor, U2, Neil Young, there are many others. I’ve been told that I occasionally sound like a Geordie Glenn Tilbrook (that’s according to the Manchedelic Roger Waters better known as Dek “MonoStone” Ham), and sometimes George Harrison, Steely Dan, Peter Gabriel, Phil Collins, Sting and David Bowie, Stephen Stills…I can dream, can’t I?
Original source: Dave Bradley Music by David Bradley.
The number of middle-aged men and women suffering a cerebral stroke has apparently risen significantly in the last decade or so. It seems that the press release from the Stroke Association making this pronouncement which has been widely reported almost verbatim by the media is based on NHS hospital admission statistics, which could have all kinds of biases and errors. I couldn’t find an actual peer-reviewed research paper to support the numbers and neither could Adam Jacobs the stats guy. It may well be just scaremongering by the media and it’s sure to boost charitable donations and raise awareness, but it’s also scary for anyone in middle age, scary enough to get you worrying and raise your blood pressure. That said, there are certain lifestyle choices that medical research suggests increase the risk of stroke, whether this latest media frenzy is based on published science or not, and so some advice on reducing one’s risk might be useful.
Thankfully, The Guardian has a nice howto on lowering your risk of suffering this often life-changing and sometimes lethal cardiovascular event.
Basically, it boils down to this:
- Stop smoking
- Exercise, but don’t overdo it, avoid straining
- Cut your calorie intake, eat smaller portions (obesity and diabetes increase risk)
- Eat a lot less salt, avoid shop-bought bread, for instance
- If you drink alcohol, spread it over the week rather than binging
- Don’t use illicit recreational drugs, including so-called “legal” highs like ecstasy, flakka and cat
- De-stress, seek help for depression
- Monitor your own blood pressure at home and see your doc if it’s consistently higher than about 140/85
I’d add another piece of advice…don’t ignore a “mini-stroke” (transient ischaemic attack (TIA)), temporary blackouts and such, if you have weird symptoms (dropping your coffee cup, slurred speech, confusion, disorientation that passes after a moment and isn’t due to alcohol use, see your doc urgently)
Alpha-PVP (α-pyrrolidinopentiophenone, alpha-PVP) is a synthetic stimulant of the cathinone class; the street drug – commonly known as flakka – is chemically similar to the illegal high MDPV (bath salts), but lacks the 3,4-methylenedioxy motif; the same difference that distinguishes methamphetamine (meth) from MDMA (ecstasy). Hype in the media have alluded to flakk leading to extreme violence, paranoid psychoses, compulsive nudity and “zombie-like” behaviour and worse. Now, researchers at The Scripps Research Institute in California have demonstrated that alpha-PVP appears to be as potent a stimulant, and therefore as addictive, as MDPV. (News source)
“There have been assertions that flakka is somehow worse than MDPV, but this study shows that the two are very similar,” explains Scripps’ Michael Taffe. “That doesn’t mean that flakka use is ‘safe’. Our data show that flakka is as potent as MDPV, making it a very good stimulant, arguably with worse addiction liability than methamphetamine.”
Aarde, Shawn M., et al. “In vivo potency and efficacy of the novel cathinone α-pyrrolidinopentiophenone and 3, 4-methylenedioxypyrovalerone: self-administration and locomotor stimulation in male rats.” Psychopharmacology (2015): 1-11.
Interesting interview in The Washington Post that corroborates what I’ve thought about all these special weightloss diet scams and con tricks made to sell books and supplements. Here are the salient points:
- When you are dieting, you actually become more likely to notice food…and it actually begins to look more appetizing and tempting and harder to resist.
- As you lose body fat, hormone levels changes, in particular concentrations of the hormones that help you feel full decrease, while hunger hormones increase.
- As you diet, your metabolism slows down so as to get the most out of the food you are eating and this means storing excess calories as fat.
Who knew? Well, lots of people knew, including many of those scammers with a diet book to sell.
Last month I reported on research into “green” coffee for SpectroscopyNOW. From a quick glance at the reader statistics it looks like it was one of my most popular articles in recent months. What is it about coffee? We’re fascinated…
Anyway, the story discussed how unroasted, green, coffee beans have become a popular alternative to regular coffee because of supposed health benefits, but there was little solid evidence of mineral availability or antioxidants from a green coffee drink that might support the claims.
Now, a team at Wroclaw University of Technology, in Poland, have used a sophisticated analytical technique* to measure how much calcium, copper, iron, magnesium and manganese ions are released into an infusion depending on whether or not the drink is made “in the cup”, using a drip filter or the Turkish coffee method. They found that calcium and magnesium are released (and so can be ingested) better than the other mineral ions but only if drip filtering or Turkish brewing was used rather than making it in the cup**. Tests on antioxidant activity also correlated with those brews from which the most calcium was leached.
*High-resolution-continuum source flame atomic absorption spectrometry
**My photo of a frothy fern in my coffee, not green coffee, unfortunately, roasted
A cutting from the Nepalese government website for the National Seismological Centre dated 2011:
“From the available data there has been no great earthquakes of magnitude >8.0 in the gap between the earthquakes of 1905 AD and 1934 AD and there is a real threat that a major earthquake may occur in this gap that will affect Western Nepal.”
A big earthquake was long overdue, and while it was magnitude 7.6, just look at the number of lives lost and the people injured. Earthquake proofing of buildings and emergency planning is feasible, but only if there’s a willingness to spend the money and if those holding the purse strings deem it worth the investment!
The best way to help in the aftermath of the earthquake is not to send stuff, nor is it to grab your backpack and head for Nepal, leave that to the logistics people and the rescue and healthcare experts. The best way for you to help is to GIVE MONEY NOW
A triumphant homecoming gig for Cambridge band Fred’s House saw a heaving Junction2 rocking to the rafters to the bands confident and big, big sound. The band old favourites at Strawberry Fair, Lodestar Festival and countless pubs and clubs in the region came home for the last steps of their Shut Up and Dance tour, delighting an enthusiastic crowd that was on its feet from the first beat with classics from their first, rootsy and folky album “Bonnie and Clyde” and introducing a few new tracks destined for their next album that reveal their strengthening songwriting skills.
The ever-smiling drummer percussionist Paul Richards provides the firm but dynamic foundations for the band with feathery flourishes interspersed between the strongest beat and partnererd perfectly by Gafin Jameson on bass guitar. The departure of lead guitarist Lachlan Golder, who played one of his final gigs with band at a private bash in Cottenham in February for Tricia, the band’s biggest fan who was 50 this year, left space for guest guitarist 18-year old Adam Chinnery who by turns was the classic country rock rhythm player and soloist and a speedy shredmeister where it was warranted by the space in some of the band’s more uptempo songs. Ali Bunclarke recently joined the housemates on keyboard, adding a subtle new layer to the overall sound and some cool fills and licks (Tricia is disappointed that I didn’t fit Ali into my photo).
Acoustic guitar player Griff, brother of Gafin and founding member, was on top form on the 6-string and vocally. And, of course, Vicki Gavin, on lead vocals is the band’s not so secret weapon, her voice never straining sweeps from the fragile rootsy sounds of their gentler repertoire to the full on raunch of their rockers. Vix and Griff, recently engaged to be married, blend beautifully with Gavin providing a subtle third harmony part (hinging on that vocal connection with Griff that you only get with siblings).
A stunning Neil Young cover was icing on the cake and there was plenty of whooping, footstamping and applause, and the occasional wolfwhistle (well done Chris) which brought the band back for an encore. From the first note, this awesome band are destined for greatness.
Husband and wife duo The Black Feathers opened wonderfully for Fred’s House. Beautiful harmonies on melancholic melodies, great guitar (with none of that silly two-handed percussive playing, just proper fingerstyle and strumming) and a unique take on English Americana.
Many species of brush-footed butterfly rely on nettles (Urtica dioica) for their caterpillars to thrive, among them, the comma (Polygonia c-album), the peacock (Inachis io), small tortoiseshell (Aglais urticae) and red admiral (Vanessa atalanta).
Sciencebase – currently rebranding weeds as wildflowers…
Apparently, puffins prefer to be deeper into rocky crevices on coastal cliff faces than razorbills (and guillemots) who cling to the edges. The puffin then has to wait until those other birds fly off, before it can get away itself to feed and socialise.
Sheer coincidence that we were visiting the East Riding of Yorkshire last week when the Royal Society for the Protection of Birds (RSPB) opened its new visitor centre at Bempton Cliffs. We approached the reserve on two walks first from North Landing on Flamborough Head where I photographed coble fishers landing and unloading their boat and then from the village of Speeton with its tiny Anglo-Saxon church (St Leonard’s and its flock of rarebreed Leicester Longwool sheep).
Bempton Cliffs plays host to England’s largest nesting colony of Northern Gannets (Sula bassana), graceful and quiet in flight and far more beautiful than their rather ugly name. The cliffs also host countless kittiwakes, razorbills, guillemots, fulmars and puffins as well as pigeons, rooks and herring gulls.