Org. and Biomol. Chem.

Syndicate content RSC - Org. Biomol. Chem. latest articles
RSC - Org. Biomol. Chem. latest articles
Updated: 1 day 22 hours ago

Highly selective and sensitive detection of glutathione using mesoporous silica nanoparticles capped with disulfide-containing oligo(ethylene glycol) chains

15 December, 2014 - 22:17

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02083A, CommunicationSameh El Sayed, Cristina Gimenez, Elena Aznar, Ramon Martinez-Manez, Felix Sancenon, Maurizio Licchelli
Mesoporous silica nanoparticles loaded with safranin O and capped with disulfide-containing oligo(ethylene glycol) chains were used for the selective and sensitive fluorimetric detection of GSH.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

A Microwave-Assisted Multicomponent Synthesis of Substituted 3,4-Dihydroquinazolinones

15 December, 2014 - 22:17
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB02417F, PaperMarc Y Stevens, Krzysztof Wieckowski, Peng Wu, Rajiv T Sawant, Luke R Odell
A microwave-assisted, multicomponent protocol for the synthesis of substituted 3,4-dihydroquinazolinones via a novel cascade imine/cyclization/aza-Henry reaction sequence is reported. Starting from o-carbamoyl aldehydes, a series of structurally diverse 3,4-dihydroquinazolinones was...
The content of this RSS Feed (c) The Royal Society of Chemistry

Understanding the Domino Reaction between 3-Chloroindoles and Methyl Coumalate yielding Carbazoles. A DFT Study.

15 December, 2014 - 22:17
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB02340D, PaperLuis R. Domingo, Jose Antonio Saez, Saeed R. Emamian
The molecular mechanism of the reaction between N-methyl-3-chloroindole and methyl coumalate yielding carbazole has been studied using DFT methods at the MPWB1K/6-311G(d,p) level in toluene. This reaction is a domino...
The content of this RSS Feed (c) The Royal Society of Chemistry

Coumarin based Gold(I)-Alkynyl Complex: A new class of Supramolecular Hydrogelator

15 December, 2014 - 22:17
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB02077D, PaperArtur J Moro, Bertrand Rome, Elisabet Aguilo, Julia Arcau, Rakesh Puttreddy, Kari Rissanen, Joao Carlos Lima, Laura Rodriquez
A phosphine-gold(I)-alkynyl-coumarin complex, [Au{7-(prop-2-ine-1-yloxy)-1-benzopyran-2-one}(DAPTA)] (1), was synthesized and the formation of long luminescent fibers in solution was characterized via Fluorescence Microscopy and Dynamic Light Scattering. The fibers presented strong blue...
The content of this RSS Feed (c) The Royal Society of Chemistry

Rapid detection of hydrazine in naphthol-fused chromenyl loop and its effectiveness in human lung cancer cells: tuning remarkable selectivity via reaction altered pathway supported by theoretical studies

15 December, 2014 - 22:17
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB01842G, PaperShyamaprosad Goswami, Avijit Kumar Das, Urmila Saha, Sibaprasad Maity, Kalyani Khanra, Nandan Bhattacharyya
Our designed and synthesized chemosensor naphthalene based chromenyl derivative (NAC) [1-(3-hydroxy-3 methyl-3H-benzo[f]chromen-2-yl) ethanone] has been used for fast ( < 30 Sec, DL = 0.14 ppb) and selective detection of...
The content of this RSS Feed (c) The Royal Society of Chemistry

A chiral borane catalyzed asymmetric hydrosilylation of imines

15 December, 2014 - 22:17

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02419B, CommunicationXiaxia Zhu, Haifeng Du
An enantioselective hydrosilylation of imines was achieved using an in situ generated chiral borane to furnish amines with up to 82% ee.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

A robust synthesis of N-glycolyl muramyl dipeptide via azidonitration/reduction

15 December, 2014 - 22:17

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02147A, PaperShuo Xing, James L. Gleason
Glycal etherification followed by azidonitration/reduction solves a difficult SN2 step in the synthesis of N-glycolyl muramyl dipeptide.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Aryl-bis-(scorpiand)-aza receptors differentiate between nucleotide monophosphates by a combination of aromatic, hydrogen bond and electrostatic interactions

15 December, 2014 - 22:17

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02084G, PaperJorge Gonzalez-Garcia, Sanja Tomic, Alberto Lopera, Lluis Guijarro, Ivo Piantanida, Enrique Garcia-Espana
Bis-scorpiands bind nucleotides in water with 10-100 [small mu ]M affinity, with selectivity: at pH 7 pyridine-scorpiand toward CMP; at pH 5 phenanthroline-scorpiand toward AMP.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Domino reaction involving the Bestmann-Ohira reagent and [small alpha],[small beta]-unsaturated aldehydes: efficient synthesis of functionalized pyrazoles

15 December, 2014 - 22:17

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02365J, PaperShakir Ahamad, Ashis Kumar Gupta, Ruchir Kant, Kishor Mohanan
A mild, efficient and rapid domino reaction involving the Bestmann-Ohira reagent (BOR) and [small alpha],[small beta]-unsaturated aldehydes has been developed for the synthesis of densely functionalized vinylpyrazoles.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

A library of 1,2,3-triazole-substituted oleanolic acid derivatives as anticancer agents: design, synthesis, and biological evaluation

15 December, 2014 - 22:17

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB01605J, PaperGaofei Wei, Weijing Luan, Shuai Wang, Shanshan Cui, Fengran Li, Yongxiang Liu, Yang Liu, Maosheng Cheng
A series of novel oleanolic acid coupled 1,2,3-triazole derivatives have been designed and synthesized by employing a Cu(I) catalyzed Huisgen 1,3-dipolar cycloaddition reaction.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Accelerated Fmoc solid-phase synthesis of peptides with aggregation-disrupting backbones

15 December, 2014 - 22:17

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02260B, PaperYi-Chao Huang, Chao-Jian Guan, Xiang-Long Tan, Chen-Chen Chen, Qing-Xiang Guo, Yi-Ming Li
In this work, we describe an accelerated solid-phase synthetic protocol for ordinary or difficult peptides involving air-bath heating and amide protection.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Bioorthogonal labelling of 3-nitrotyrosine in peptides and proteins through diazotisation mediated azidation

15 December, 2014 - 22:17

Org. Biomol. Chem., 2015, 13,374-378
DOI: 10.1039/C4OB02133A, CommunicationJohn Y. Ng, Jason W. H. Wong
A bioorthogonal method of transforming 3-nitrotyrosine to 3-azidotyrosine is described, providing new opportunities to study 3-nitrotyrosine in biological samples.
The content of this RSS Feed (c) The Royal Society of Chemistry

Anion binding by biotin[6]uril in water

15 December, 2014 - 22:17

Org. Biomol. Chem., 2015, 13,369-373
DOI: 10.1039/C4OB02211D, CommunicationMicke Lisbjerg, Bjarne E. Nielsen, Birgitte O. Milhoj, Stephan P. A. Sauer, Michael Pittelkow
We show that the newly discovered 6 + 6 biotin-formaldehyde macrocycle Biotin[6]uril binds a variety of anionic guest molecules in water. We discuss how and why the anions are bound based on data obtained using NMR spectroscopy, mass spectrometry, isothermal titrations calorimetry (ITC), computational calculations and single crystal X-ray crystallography.
The content of this RSS Feed (c) The Royal Society of Chemistry

Cucurbituril-based supramolecular engineered nanostructured materials

15 December, 2014 - 22:17

Org. Biomol. Chem., 2015, 13,330-347
DOI: 10.1039/C4OB02065K, Review ArticleSinem Gurbuz, Muazzam Idris, Donus Tuncel
Nanostructured materials, including nanoparticles, nanocomposites, vesicles, and rods, have been prepared by taking advantage of the interesting features of cucurbituril homologues.
The content of this RSS Feed (c) The Royal Society of Chemistry

The direct electrophilic cyanation of [small beta]-keto esters and amides with cyano benziodoxole

15 December, 2014 - 22:17

Org. Biomol. Chem., 2015, 13,365-368
DOI: 10.1039/C4OB02032D, CommunicationYao-Feng Wang, Jiashen Qiu, Dejie Kong, Yongtao Gao, Feipeng Lu, Pran Gopal Karmaker, Fu-Xue Chen
Electrophilic cyanating agent C1 accomplishes the direct cyanation of [small beta]-keto esters and amides without any catalyst and base.
The content of this RSS Feed (c) The Royal Society of Chemistry

Fe-promoted radical cyanomethylation/arylation of arylacrylamides to access oxindoles via cleavage of the sp3 C-H of acetonitrile and the sp2 C-H of the phenyl group

15 December, 2014 - 22:17

Org. Biomol. Chem., 2015, 13,361-364
DOI: 10.1039/C4OB02172J, CommunicationChangduo Pan, Honglin Zhang, Chengjian Zhu
Radical cyanomethylation/arylation of arylacrylamides to access oxindoles with acetonitrile as a radical precursor is described, involving dual C-H bond functionalization.
The content of this RSS Feed (c) The Royal Society of Chemistry

Rhodium(II)-catalyzed intramolecular formal [4 + 3] cycloadditions of dienyltriazoles: rapid access to fused 2,5-dihydroazepines

15 December, 2014 - 22:17

Org. Biomol. Chem., 2015, 13,612-619
DOI: 10.1039/C4OB01910E, PaperYu Tian, Yuanhao Wang, Hai Shang, Xudong Xu, Yefeng Tang
Rh(II)-catalyzed intramolecular formal [4 + 3] cycloadditions of dienyltriazoles have been developed, which enable the efficient synthesis of various fused 2,5-dihydroazepines.
The content of this RSS Feed (c) The Royal Society of Chemistry

A highly efficient and eco-friendly method for the synthesis of 1,3-indandione ring-fused 3-oxindoles bearing two contiguous quaternary stereocenters via an aldol reaction in aqueous media

15 December, 2014 - 22:17

Org. Biomol. Chem., 2015, 13,601-611
DOI: 10.1039/C4OB02103G, PaperXiong-Li Liu, Bo-Wen Pan, Wen-Hui Zhang, Chao Yang, Jun Yang, Yang Shi, Ting-Ting Feng, Ying Zhou, Wei-Cheng Yuan
The synthesis and antitumor activity evaluation of 1,3-indandione ring-fused 3-oxindoles.
The content of this RSS Feed (c) The Royal Society of Chemistry

Structural insight into the aggregation of L-prolyl dipeptides and its effect on organocatalytic performance

15 December, 2014 - 22:17

Org. Biomol. Chem., 2015, 13,592-600
DOI: 10.1039/C4OB02003K, PaperCristina Berdugo, Beatriu Escuder, Juan F. Miravet
NMR and organocatalytic studies of four dipeptides derived from L-proline are described.
The content of this RSS Feed (c) The Royal Society of Chemistry

Novel synthesis of 5-methyl-5,10-dihydroindolo[3,2-b]indoles by Pd-catalyzed C-C and two-fold C-N coupling reactions

15 December, 2014 - 22:17

Org. Biomol. Chem., 2015, 13,583-591
DOI: 10.1039/C4OB01723D, PaperTran Quang Hung, Soren Hancker, Alexander Villinger, Stefan Lochbrunner, Tuan Thanh Dang, Aleksej Friedrich, Wolfgang Breitsprecher, Peter Langer
A series of 5,10-dihydroindolo[3,2-b]indoles was successfully prepared by an efficient two-step strategy.
The content of this RSS Feed (c) The Royal Society of Chemistry

WebElements: the periodic table on the WWW [http://www.webelements.com/]

Copyright 1993-2011 Mark Winter [The University of Sheffield and WebElements Ltd, UK]. All rights reserved.