Org. and Biomol. Chem.

Syndicate content RSC - Org. Biomol. Chem. latest articles
RSC - Org. Biomol. Chem. latest articles
Updated: 3 hours 54 min ago

Synthesis of novel tryptamine-based macrocycles using an Ugi 4-CR/microwave assisted click-cycloaddition reaction protocol

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C5OB00067J, CommunicationLizbeth Chavez-Acevedo, Luis D. Miranda
A practical synthesis of novel tryptamine-based macrocycles using an Ugi 4-CR/click-cycloaddition sequential reaction protocol is described.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Palladium-catalyzed oxidative C-H/C-H cross-coupling of 1-substituted 1,2,3-triazoles with furans and thiophenes

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C5OB00102A, PaperXin Yu, ZhenDong Huang, Wei Liu, SuPing Shi, ChunXiang Kuang
Palladium-catalyzed heteroarylation of 1-substituted 1,2,3-triazoles with furans and thiophenes has been developed in the presence of pyridine and Ag2CO3.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Chirality extension of an oxazine building block en route to total syntheses of (+)-hyacinthacine A2 and sphingofungin B

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C5OB00251F, PaperSeok-Hwi Park, Xiangdan Jin, Jong-Cheol Kang, Changyoung Jung, Seong-Soo Kim, Sung-Soo Kim, Kee-Young Lee, Won-Hun Ham
Concise total syntheses of (+)-hyacinthacine A2 and sphingofungin B were achieved by palladium(0)-catalyzed intramolecular oxazine formation and diastereoselective nucleophilic additions.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Peptide-DNA conjugates as tailored bivalent binders of the oncoprotein c-Jun

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C5OB00318K, PaperElena Pazos, Cecilia Portela, Cristina Penas, M. Eugenio Vazquez, Jose L. Mascarenas
A designed disrupter of the DNA complexes of oncoproteins Fos and Jun is reported.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Near-infrared emission of dibenzoxanthenium and its application in the design of nitric oxide probes

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C5OB00042D, PaperWu Liu, Chen Fan, Ru Sun, Yu-Jie Xu, Jian-Feng Ge
The application of a diaminodibenzoxanthenium skeleton in chemosensors was reported, and it can work with near-infrared excitation and near-infrared emission.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Facile synthesis of spirooxindole-pyrazolines and spirobenzofuranone-pyrazolines and their fungicidal activity

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C5OB00258C, PaperChangjiang Yang, Juanjuan Li, Rong Zhou, Xiangyu Chen, Yunpeng Gao, Zhengjie He
A new and facile synthetic method is developed for biologically important spirooxindole-pyrazolines and spirobenzofuranone-pyrazolines.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Efficient access to enantiopure 1,3-disubstituted isoindolines from selective catalytic fragmentation of an original desymmetrized rigid overbred template

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C5OB00229J, PaperGanesh Pandey, Rajesh Varkhedkar, Divya Tiwari
Enantiopure 1,3-disubstituted isoindolines are synthesized from selective C-C bond fragmentation of a rigid overbred template, obtained through an asymmetric desymmetrization reaction.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Regioselective solid-phase synthesis of N-mono-hydroxylated and N-mono-methylated acylpolyamine spider toxins using an 2-(ortho-nitrophenyl)ethanal-modified resin

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C5OB00108K, PaperDenise Pauli, Stefan Bienz
Spider toxins such as AG432g and LF487A were divergently prepared by SPS and used for correlation with the natural products.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Synthesis of 2-anilinopyridyl-triazole conjugates as antimitotic agents

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C5OB00232J, PaperAhmed Kamal, A. V. Subba Rao, M. V. P. S. Vishnuvardhan, T. Srinivas Reddy, Konderu Swapna, Chandrakant Bagul, N. V. Subba Reddy, Vunnam Srinivasulu
The newly synthesized 2-anilinopyridyl-triazole conjugates with excellent pharmacological profile could serve as leads for further optimization.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

An IDB-containing low molecular weight short peptide as an efficient DNA cleavage reagent

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02518K, PaperChunying Ma, Huan Chen, Chao Li, Jin Zhang, Renzhong Qiao
We present poly(aspartic acid) grafting bis-amine conjugates as artificial nucleases, which can effectively induce double-strand DNA cleavage.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Sodium periodate mediated oxidative transformations in organic synthesis

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C5OB00238A, Review ArticleArumugam Sudalai, Alexander Khenkin, Ronny Neumann
The investigation of new oxidative transformations for the synthesis of carbon-heteroatom and heteroatom-heteroatom bonds is of fundamental importance in the synthesis of numerous bioactive molecules and fine chemicals.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

N-Branched acyclic nucleoside phosphonates as monomers for the synthesis of modified oligonucleotides

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02265C, PaperDana Hockova, Sarka Rosenbergova, Petra Menova, Ondrej Pav, Radek Pohl, Pavel Novak, Ivan Rosenberg
The solid phase synthesis of nonamers containing a highly flexible acyclic central unit was performed and their hybridization properties were evaluated.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Synthesis and complementary self-association of novel lipophilic [small pi]-conjugated nucleoside oligomers

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C5OB00098J, PaperJ. Camacho-Garcia, C. Montoro-Garcia, A. M. Lopez-Perez, N. Bilbao, S. Romero-Perez, D. Gonzalez-Rodriguez
A series of lipophilic nucleosides comprising natural and non-natural bases that are [small pi]-conjugated to a short oligophenylene-ethynylene fragment has been synthesized and their respective association constants measured.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Visible-light-induced cleavage of 4-[small alpha]-amino acid substituted naphthalimides and its application in DNA photocleavage

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, 13,3931-3935
DOI: 10.1039/C5OB00302D, PaperJin Zhou, Canliang Fang, Ying Liu, Yao Zhao, Nan Zhang, Xiangjun Liu, Fuyi Wang, Dihua Shangguan
4-[small alpha]-Amino acid substituted naphthalimides can be photocleaved at the C-N bond between the 4-amino and the amino acid residue under visible light irradiation, releasing a fluorophore, 4-aminonaphthalimide.
The content of this RSS Feed (c) The Royal Society of Chemistry

Manganese catalysed sulfenylation of N-methyl amides with arenesulfonyl hydrazides

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, 13,3878-3881
DOI: 10.1039/C5OB00133A, CommunicationJinwei Sun, Yi Wang, Yi Pan
A convenient oxidative sulfenylation method for the formation of various sulfenyl amides has been reported.
The content of this RSS Feed (c) The Royal Society of Chemistry

Rh(III)-catalyzed direct C-H/C-H cross-coupling of quinones with arenes assisted by a directing group: identification of carbazole quinones as GSK[small beta] inhibitors

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, 13,3918-3923
DOI: 10.1039/C4OB02624A, PaperYoungtaek Moon, Yujeong Jeong, Daehyuk Kook, Sungwoo Hong
Rh-catalyzed direct cross-coupling of various (hetero)arenes with quinones is developed. This protocol is effective for a broad range of substrates and a wide range of directing groups.
The content of this RSS Feed (c) The Royal Society of Chemistry

Transition-metal-free decarboxylation of dimethyl malonate: an efficient construction of [small alpha]-amino acid esters using TBAI/TBHP

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, 13,3982-3987
DOI: 10.1039/C5OB00109A, PaperJie Zhang, Ying Shao, Yaxiong Wang, Huihuang Li, Dongmei Xu, Xiaobing Wan
A new strategy has been developed for the synthesis of [small alpha]-amino acid esters via a tandem hydrolysis/decarboxylation/nucleophilic substitution using TBAI/TBHP.
The content of this RSS Feed (c) The Royal Society of Chemistry

An efficient synthesis of quinolines via copper-catalyzed C-N cleavage

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, 13,3924-3930
DOI: 10.1039/C5OB00075K, PaperLong-Yi Xi, Ruo-Yi Zhang, Lei Zhang, Shan-Yong Chen, Xiao-Qi Yu
An efficient method to synthesize substituted quinolines from ketones and 2-amino benzylamines is described.
The content of this RSS Feed (c) The Royal Society of Chemistry

Synthesis of phenstatin/isocombretastatin-chalcone conjugates as potent tubulin polymerization inhibitors and mitochondrial apoptotic inducers

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, 13,3963-3981
DOI: 10.1039/C4OB02606C, PaperAhmed Kamal, G. Bharath Kumar, M. V. P. S. Vishnuvardhan, Anver Basha Shaik, Vangala Santhosh Reddy, Rasala Mahesh, Ibrahim Bin Sayeeda, Jeevak Sopanrao Kapure
A series of phenstatin/isocombretastatin-chalcones were synthesized and screened for their cytotoxic activity.
The content of this RSS Feed (c) The Royal Society of Chemistry

Harmony of CdI2 with CuBr for the one-pot synthesis of optically active [small alpha]-allenols

22 March, 2015 - 22:54

Org. Biomol. Chem., 2015, 13,4080-4089
DOI: 10.1039/C4OB02673J, PaperJiasheng Zhang, Juntao Ye, Shengming Ma
A highly efficient one-pot synthesis of chiral [small alpha]-allenols from propargylic alcohols, aldehydes and pyrrolidine induced by CuBr and (R,Ra)-N-PINAP or (R,Sa)-N-PINAP and CdI2 has been developed.
The content of this RSS Feed (c) The Royal Society of Chemistry

WebElements: the periodic table on the WWW [http://www.webelements.com/]

Copyright 1993-2011 Mark Winter [The University of Sheffield and WebElements Ltd, UK]. All rights reserved.