Org. and Biomol. Chem.
RSC - Org. Biomol. Chem. latest articles
Updated: 1 day 2 hours ago
Cooperative enhancement of optical nonlinearities in a porphyrin derivative bearing a pyrimidine chromophore at the periphery
DOI: 10.1039/C3OB40323H, PaperAijian Wang, Lingliang Long, Suci Meng, Xiufen Li, Wei Zhao, Yinglin Song, Marie P. Cifuentes, Mark G. Humphrey, Chi Zhang
Enhanced optical nonlinearities were observed for compound 6 due to a combination of different nonlinear mechanisms.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
Catalyst-controlled switchable phosphination of [small alpha]-diazoesters
DOI: 10.1039/C3OB40429C, CommunicationHonglai Jiang, Hongming Jin, Ablimit Abdukader, Aijun Lin, Yixiang Cheng, Chengjian Zhu
A catalyst-controlled switchable phosphination of [small alpha]-diazoesters has been developed by using DBU and copper as catalysts. It provided an efficient synthetic method for the construction of various phosphorus compounds via the formation of N-P and C-P bonds.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
Aerobic oxidation of indole carbinols using Fe(NO3)3[middle dot]9H2O/TEMPO/NaCl as catalysts
DOI: 10.1039/C3OB40226F, PaperJinxian Liu, Shengming Ma
A practical method for the aerobic oxidation of indole carbinols using Fe(NO3)3[middle dot]9H2O/TEMPO/NaCl as catalysts under mild conditions was developed, affording aldehydes or ketones in good to excellent yields.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
Dibenzotetraaza[14]annulene-adenine conjugate recognizes complementary poly dT among ss-DNA/ss-RNA sequences
DOI: 10.1039/C3OB40519B, PaperMarijana Radic Stojkovic, Marko Skugor, Sanja Tomic, Marina Grabar, Vilko Smrecki, Lukasz Dudek, Jaroslaw Grolik, Julita Eilmes, Ivo Piantanida
DBTAA-(CH2)3-adenine: the first small molecule able to recognize consecutive oligo dT sequence by affinity and specific chirooptical (ICD) response.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
Synthesis of the decalin core of codinaeopsin via an intramolecular Diels-Alder reaction
DOI: 10.1039/C3OB40480C, PaperMani Ramanathan, Chun-Jui Tan, Wen-Jung Chang, Hui-Hsu Gavin Tsai, Duen-Ren Hou
The highly substituted decalin core of codinaeopsin was synthesized via an intramolecular Diels-Alder reaction.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
C [rightward arrow] N and N [rightward arrow] C solution phase peptide synthesis using the N-acyl 4-nitrobenzenesulfonamide as protection of the carboxylic function
DOI: 10.1039/C3OB40169C, PaperRosaria De Marco, Mariagiovanna Spinella, Anna De Lorenzo, Antonella Leggio, Angelo Liguori
The N-acyl 4-nitrobenzenesulfonamides have been used as "activatable protection" of the carboxylic function in solution phase peptide synthesis for the obtainment of peptides both in the C [rightward arrow] N and in the N [rightward arrow] C direction.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
Design and synthesis of tryptophan containing dipeptide derivatives as formyl peptide receptor 1 antagonist
DOI: 10.1039/C3OB40215K, PaperTsong-Long Hwang, Chih-Hao Hung, Ching-Yun Hsu, Yin-Ting Huang, Yu-Chi Tsai, Pei-Wen Hsieh
A series of tryptophan containing dipeptides were synthesized and their anti-inflammatory effects and underlying mechanisms were investigated in human neutrophils.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
On the stability of [(uracil)2-Cu]2+ complexes in the gas phase. Different pathways for the formation of [(uracil-H)(uracil)-Cu]+ monocations
DOI: 10.1039/C3OB40450A, PaperOriana Brea, Manuel Yanez, Otilia Mo, Al Mokhtar Lamsabhi
Cu2+ leads to the deprotonation of one of the uracil units within the [(uracil)2-Cu]2+ doubly-charged complexes and to a simultaneous enolization of the other uracil moiety.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
In-peptide synthesis of di-oxazolidinone and dehydroamino acid-oxazolidinone motifs as [small beta]-turn inducers
DOI: 10.1039/C3OB40357B, PaperRossella De Marco, Arianna Greco, Sebastiano Rupiani, Alessandra Tolomelli, Claudia Tomasini, Silvia Pieraccini, Luca Gentilucci
Constraining a peptide in a snap: linear peptides 1 give rise in a single step to sequences Oxd2-Oxd3 (2) or [capital Delta]Abu2-Oxd3 (3), characterized by well defined extended or folded conformations.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
Regioselective di- and tetra-functionalisation of [gamma]-cyclodextrin using capping methodology
DOI: 10.1039/C3OB40234G, PaperMatthieu Jouffroy, Dominique Armspach, Dominique Matt, Loic Toupet
[gamma]-Cyclodextrin was regioselectively functionalised using the dialkylating capping reagent 1,3-bis[bis(4-tert-butylphenyl)chloro-methyl]benzene.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
Structural modifications of (Z)-3-(2-aminoethyl)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione that improve selectivity for inhibiting the proliferation of melanoma cells containing active ERK signaling
DOI: 10.1039/C3OB40199E, PaperKwan-Young Jung, Ramin Samadani, Jay Chauhan, Kerrick Nevels, Jeremy L. Yap, Jun Zhang, Shilpa Worlikar, Maryanna E. Lanning, Lijia Chen, Mary Ensey, Sagar Shukla, Rosene Salmo, Geoffrey Heinzl, Caryn Gordon, Troy Dukes, Alexander D. MacKerell, Jr., Paul Shapiro, Steven Fletcher
Cell-based SAR of an ERK docking domain inhibitor
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
From N-benzoylpyridinium imides to pyrazolo[1,5-a]pyridines: a mechanistic discussion on a stoichiometric Cu protocol
DOI: 10.1039/C3OB40448J, PaperLin Ling, Jingqing Chen, Jiahui Song, Yuhai Zhang, Xinqian Li, Lijuan Song, Feng Shi, Yuxue Li, Chunrui Wu
A Cu-mediated process that couples N-benzoylpyridinium imides and terminal alkynes employs stoichiometric Cu(OAc)2 as both the mediator and the oxidant. Extensive DFT calculations suggest a Cu(III) intermediate via Cu(II) disproportionation.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
Theoretical investigation of the Diels-Alder reactions of unsaturated boronates
DOI: 10.1039/C3OB40146D, PaperNicolas Grimblat, Silvina C. Pellegrinet
Concerted normal electron-demand Diels-Alder reactions with asynchronous TSs and weak [4 + 3] C-B SOIs for boronates.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
Scope and limitations of the Heck-Matsuda-coupling of phenol diazonium salts and styrenes: a protecting-group economic synthesis of phenolic stilbenes
DOI: 10.1039/C3OB40420J, PaperBernd Schmidt, Nelli Elizarov, Rene Berger, Frank Holter
4[prime or minute]-Hydroxy stilbenes were synthesized from 4-phenol diazonium salts via the Heck-Matsuda coupling without using OH-protecting groups for the arylating agent.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
Transition metal-catalyzed functionalization of pyrazines
DOI: 10.1039/C3OB40460A, PerspectiveNicolai I. Nikishkin, Jurriaan Huskens, Willem Verboom
This review deals with recent progress in the field of transition metal-catalyzed cross-coupling reactions on pyrazine systems.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
Silver-catalyzed amidation of benzoylformic acids with tertiary amines via selective carbon-nitrogen bond cleavage
DOI: 10.1039/C3OB40619A, PaperXiaobin Zhang, Wenchao Yang, Lei Wang
A novel approach to [small alpha]-ketoamides using tertiary amines as nitrogen group sources via C-N bond cleavage has been developed.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
One-pot synthesis of branched oligosaccharides by use of galacto- and mannopyranosyl thioglycoside diols as key glycosylating agents
DOI: 10.1039/C3OB40421H, PaperXing-Yong Liang, Qiang-Wei Liu, Hua-Chao Bin, Jin-Song Yang
We describe in this paper the efficient four-component one-pot synthesis of three fully protected oligosaccharides 22, 36, and 50 with di-branched structures by employing D-galacto- and mannopyranosyl thioglycoside diols as central glycosylating agents.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
An efficient coupling of N-tosylhydrazones with 2-halopyridines: synthesis of 2-[small alpha]-styrylpyridines endowed with antitumor activity
DOI: 10.1039/C3OB40263K, PaperMarie Lawson, Abdallah Hamze, Jean-Francois Peyrat, Jerome Bignon, Joelle Dubois, Jean-Daniel Brion, Mouad Alami
PdCl2(MeCN)2 in combination with DPPF or tBu2MeP-HBF4 catalyzes the reaction of N-tosylhydrazones with various 2-halopyridines to provide the 2-alpha-styrylpyridines olefins of biological interest.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
A palladium-catalyzed coupling of 3-chloroquinoxalinones with various nitrogen-containing nucleophiles
DOI: 10.1039/C3OB40338F, PaperEtienne Brachet, Jean-Francois Peyrat, Jean-Daniel Brion, Samir Messaoudi, Mouad Alami
The Pd(OAc)2/Xantphos catalyst system effectively catalyzes the coupling of 3-chloroquinoxalinones with a series of nitrogen-containing nucleophiles in the presence of K2CO3 in dioxane at 90 [degree]C.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry
Iron-catalysed oxidative amidation of alcohols with amines
DOI: 10.1039/C3OB40170G, PaperSilvia Gaspa, Andrea Porcheddu, Lidia De Luca
A new iron-catalysed oxidative amidation of differently substituted benzylic alcohols with mono- and di-substituted amines was developed.
The content of this RSS Feed (c) The Royal Society of Chemistry
Categories: Royal Society of Chemistry