Org. and Biomol. Chem.

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RSC - Org. Biomol. Chem. latest articles
Updated: 2 days 8 min ago

[gamma]-Cyclodextrin modulates the chemical reactivity by multiple complexation

11 January, 2015 - 05:17

Org. Biomol. Chem., 2015, 13,1213-1224
DOI: 10.1039/C4OB02113D, PaperJ. Fernandez-Rosas, M. Pessego, M. Cepeda-Plaza, N. Basilio, M. Parajo, P. Rodriguez-Dafonte, L. Garcia-Rio
Multiple recognition by cooperative/competitive mechanisms to form a 1 : 1 : 1 inclusion complex plays a crucial role in determining the chemical reactivity in the [gamma]-CD cavity.
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Catalyst-free synthesis of 2-aryl-1,2-dihydro-quinazolin-4(1H)-thiones from 2-aminobenzothio-amides and aldehydes in water

11 January, 2015 - 05:17

Org. Biomol. Chem., 2015, 13,1150-1158
DOI: 10.1039/C4OB02207F, PaperStefan Oschatz, Tom Brunzel, Xiao-Feng Wu, Peter Langer
A convenient and facile procedure for the synthesis of dihydroquinazolinthiones from 2-aminobenzothioamide with aldehydes has been developed. The reactions took place in water without the need of any additive.
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Design and synthesis of Troger's base ditopic receptors: host-guest interactions, a combined theoretical and experimental study

11 January, 2015 - 05:17

Org. Biomol. Chem., 2015, 13,1141-1149
DOI: 10.1039/C4OB02266A, PaperManda Bhaskar Reddy, Myadaraboina Shailaja, Alla Manjula, Joseph Richard Premkumar, Garikapati Narahari Sastry, Katukuri Sirisha, Akella Venkata Subrahmanya Sarma
The host-guest interaction between flexible ditopic receptors and bisammonium ion has been investigated experimentally and computationally. The conformation folding of guest bisammonium ion molecules leads to the oscillation of the host-guest interaction.
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The synthesis of [18F]pitavastatin as a tracer for hOATP using the Suzuki coupling

11 January, 2015 - 05:17

Org. Biomol. Chem., 2015, 13,1113-1121
DOI: 10.1039/C4OB01953A, PaperYusuke Yagi, Hiroyuki Kimura, Kenji Arimitsu, Masahiro Ono, Kazuya Maeda, Hiroyuki Kusuhara, Tetsuya Kajimoto, Yuichi Sugiyama, Hideo Saji
Fluorine-18 labeled radiotracers, such as [18F]fluorodeoxyglucose, can be used as practical diagnostic agents in positron emission tomography (PET).
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The development of a complementary pathway for the synthesis of aliskiren

11 January, 2015 - 05:17

Org. Biomol. Chem., 2015, 13,1133-1140
DOI: 10.1039/C4OB01963F, PaperLe-Le Li, Jin-Ying Ding, Lian-Xun Gao, Fu-She Han
We present an alternative pathway for the synthesis of aliskiren by applying the Evans chiral auxiliary-aided asymmetric allylation and the Julia-Kocienski olefination as the key transformations.
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Modulation of the charge transfer and photophysical properties in non-fused tetrathiafulvalene-benzothiadiazole derivatives

11 January, 2015 - 05:17

Org. Biomol. Chem., 2015, 13,1040-1047
DOI: 10.1039/C4OB02100B, PaperFlavia Pop, Sabine Seifert, Jihane Hankache, Jie Ding, Andreas Hauser, Narcis Avarvari
Stille and Sonogashira coupling strategies allowed the preparation of luminescent TTF-benzothiadiazole donor-acceptor compounds with direct linkage or an acetylenic spacer.
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Tuning the pH-triggered self-assembly of dendritic peptide amphiphiles using fluorinated side chains

11 January, 2015 - 05:17

Org. Biomol. Chem., 2015, 13,1030-1039
DOI: 10.1039/C4OB02185A, PaperRalph Appel, Sebastian Tacke, Jurgen Klingauf, Pol Besenius
We report the synthesis of a series of anionic dendritic peptide amphiphiles of increasing hydrophobic character and describe their self-assembly into supramolecular nanorods using pH and ionic strength dependent state diagrams.
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