Org. and Biomol. Chem.

Syndicate content RSC - Org. Biomol. Chem. latest articles
RSC - Org. Biomol. Chem. latest articles
Updated: 16 hours 50 min ago

Comparative analysis of cross strand aromatic-Phe interactions in designed peptide [small beta]-hairpins

8 January, 2014 - 11:17
Org. Biomol. Chem., 2013, Accepted Manuscript
DOI: 10.1039/C3OB42247J, PaperKamlesh Madhusudan Makwana, Radhakrishnan Mahalakshmi
The mode(s), geometry and strength of interaction of the three aromatic amino acids, namely Phe, Tyr and Trp, with the benzyl side chain of Phe, at the non-hydrogen bonding position...
The content of this RSS Feed (c) The Royal Society of Chemistry

Syntheses and Photophysical Properties of BF2 Complexes of Curcumin Analogs

8 January, 2014 - 11:17
Org. Biomol. Chem., 2013, Accepted Manuscript
DOI: 10.1039/C3OB42201A, PaperGuifeng Bai, Changjiang Yu, Chi Cheng, Erhong Hao, Yun Wei, Xiaolong Mu, Lijuan Jiao
Stable tetracoordinated organoboron complexes as classic fluorescent molecules have found various applications in material and medical sciences. A new class of curcumin-BF2 complexes has been prepared from the condensation of...
The content of this RSS Feed (c) The Royal Society of Chemistry

Catalytic and mechanistic studies into the epoxidation of styrenes using manganese complexes of structurally similar polyamine ligands

6 January, 2014 - 10:54
Org. Biomol. Chem., 2013, Accepted Manuscript
DOI: 10.1039/C3OB42274G, PaperMichael Watkinson, Gennadiy Ilyashenko, Thomas Follier, Rawan Al-Safadi, Majid Motevalli, Giorgio De Faveri
Two structurally similar polyamine ligands (7 and 8) have been prepared, which differ only by the presence of either a secondary or tertiary nitrogen donor within their N5 donor set....
The content of this RSS Feed (c) The Royal Society of Chemistry

Phenazine Antibiotic Inspired Discovery of Potent Bromophenazine Antibacterial Agents against Staphylococcus aureus and Staphylococcus epidermidis

6 January, 2014 - 10:54
Org. Biomol. Chem., 2013, Accepted Manuscript
DOI: 10.1039/C3OB42416B, CommunicationNicholas Borrero, Fang Bai, Cristian Perez, Benjamin Doung, James Rocca, Shouguang Jin, Robert William Huigens
Nearly all clinically used antibiotics have been 1.) discovered from microorganisms 2.) using phenotype screens to identify inhibitors of bacterial growth. The effectiveness of these antibiotics is attributed to their...
The content of this RSS Feed (c) The Royal Society of Chemistry

Ketones as Electrophiles in Two Component Baylis-Hillman Reaction: A Facile One-Pot Synthesis of Substituted Indolizines

6 January, 2014 - 10:54
Org. Biomol. Chem., 2013, Accepted Manuscript
DOI: 10.1039/C3OB42064G, CommunicationDeevi Basavaiah, Gorre Veeraraghavaiah, Satpal Singh Badsara
2-Alkanoyl(aroyl)-pyridines have been successfully used for coupling with alkyl vinyl ketones under the influence of TMSOTf providing a facile protocol for synthesis of substituted indolizines, thus demonstrating the applications of...
The content of this RSS Feed (c) The Royal Society of Chemistry

Rhodium-Catalyzed Three-Component Reaction of 3-Diazooxindoles with Indoles and Isatin-Derived Ketimines: A Facile and Versatile Approach to Functionalized 3,3',3''-Trisindoles

6 January, 2014 - 10:54
Org. Biomol. Chem., 2013, Accepted Manuscript
DOI: 10.1039/C3OB42283F, PaperMin Shi, Xiang-Ying Tang, Liangyong Mei
A simple, facile and efficient Rh2(OAc)4-catalyzed three-component reaction of 3-diazooxindoles with indoles and isatin-derived N-Boc ketimines towards a variety of functionalized 3,3',3''-trisindoles in high yields with moderate to excellent diastereoselectivities...
The content of this RSS Feed (c) The Royal Society of Chemistry

Asymmetric Mannich reaction between (S)-N-(tert-butanesulfinyl)-3,3,3-trifluoroacetaldimine and malonic acid derivatives. Stereodivergent synthesis of (R)- and (S)-3-amino-4,4,4-trifluorobutanoic acids

6 January, 2014 - 10:54
Org. Biomol. Chem., 2013, Accepted Manuscript
DOI: 10.1039/C3OB42425A, PaperNorio Shibata, Takayuki Nishimine, Naoyuki Shibata, Etsuko Tokunaga, Kosuke Kawada, Takumi Kagawa, Jose Luis Acena, Alexander E. Sorochinsky, Vadim A Soloshonok
Inorganic as well as organic base catalysis was found to be effective for diastereoselective Mannich additions of malonic acid derivatives to (SS)-N-(tert-butanesulfinyl)-3,3,3-trifluoroacetaldimine. In the presence of catalytic amounts of inorganic...
The content of this RSS Feed (c) The Royal Society of Chemistry

NH-Type of chiral Ni(II) complexes of glycine Schiff base: design, structural evaluation, reactivity and synthetic applications

6 January, 2014 - 10:54
Org. Biomol. Chem., 2013, Accepted Manuscript
DOI: 10.1039/C3OB41959B, PaperMackenzie Bergagnini, Kazunobu Fukushi, Jianlin Han, Norio Shibata, Christian Roussel, Trevor K Ellis, Jose Luis Acena, Vadim A Soloshonok
The work being reported here deals with the design of a new type of "N-H" Ni(II) complexes of glycine Schiff bases and study general aspects of their reactivity. It was...
The content of this RSS Feed (c) The Royal Society of Chemistry

Properties of 5- and/or 2-modified 2´-O-cyanoethyl uridine residue: 2´-O-cyanoethyl-5-propynyl-2-thiouridine as an efficient duplex stabilizing component

6 January, 2014 - 10:54
Org. Biomol. Chem., 2013, Accepted Manuscript
DOI: 10.1039/C3OB41983E, PaperYoshiaki Masaki, Kunihiro Hirai, Ryuta Miyasaka, Takashi Kanamori, Hirosuke Tsunoda, Akihiro Ohkubo, Kohji Seio, Mitsuo Sekine
We systematically synthesized eight types of 5-and/or 2-modified uridine derivatives and evaluated their effect on duplex stability. The incorporation of 2´-O-cyanoethyl-2-thio-5-propynyluridine (p5s2UOCE) into RNA was significantly effective for stabilization of...
The content of this RSS Feed (c) The Royal Society of Chemistry

Napyradiomycins CNQ525.510B and A80915C target the Hsp90 paralogue Grp94

6 January, 2014 - 10:54

Org. Biomol. Chem., 2014, 12,418-423
DOI: 10.1039/C3OB41355A, CommunicationLauge Farnaes, James J. La Clair, William Fenical
The intracellular localization and target of the napyradiomycin congeners CNQ525.510B and A80815C were explored using an immunoaffinity fluorescence (IAF) approach.
The content of this RSS Feed (c) The Royal Society of Chemistry

Gadolinium-binding cyclic hexapeptoids: synthesis and relaxometric properties

6 January, 2014 - 10:54

Org. Biomol. Chem., 2014, 12,424-431
DOI: 10.1039/C3OB42029A, PaperChiara De Cola, Gaetano Fiorillo, Alessandra Meli, Silvio Aime, Eliana Gianolio, Irene Izzo, Francesco De Riccardis
Cyclic hexapeptoids are able to efficiently bind Gd3+ ions. Their thermodynamic stabilities have been assessed by 1H-relaxometric investigations.
The content of this RSS Feed (c) The Royal Society of Chemistry

Substituent effects on the turn-on kinetics of rhodamine-based fluorescent pH probes

6 January, 2014 - 10:54

Org. Biomol. Chem., 2014, 12,526-533
DOI: 10.1039/C3OB42089B, PaperWilliam L. Czaplyski, Grace E. Purnell, Courtney A. Roberts, Rebecca M. Allred, Elizabeth J. Harbron
The kinetics and intensity of the fluorescence turn-on response of rhodamine spirolactam pH probes are found to be controlled by the electronics of the spirolactam.
The content of this RSS Feed (c) The Royal Society of Chemistry

More than one non-canonical phosphodiester bond in the G-tract: formation of unusual parallel G-quadruplex structures

6 January, 2014 - 10:54

Org. Biomol. Chem., 2014, 12,534-540
DOI: 10.1039/C3OB41712C, PaperAntonella Virgilio, Veronica Esposito, Luciano Mayol, Aldo Galeone
An investigation concerning the formation of unusual quadruplexes by 5[prime or minute]TGGGGT3[prime or minute] analogues containing more than one non-canonical phosphodiester bond in the G-run, is reported.
The content of this RSS Feed (c) The Royal Society of Chemistry

Protein-mediated dethreading of a biotin-functionalised pseudorotaxane

6 January, 2014 - 10:54

Org. Biomol. Chem., 2014, 12,511-516
DOI: 10.1039/C3OB41612G, PaperStuart T. Caldwell, Catherine Maclean, Mathis Riehle, Alan Cooper, Margaret Nutley, Gouher Rabani, Brian Fitzpatrick, Vincent M. Rotello, Brian O. Smith, Belal Khaled, Patrice Woisel, Graeme Cooke
We report the ability of biotin-binding proteins to mediate pseudorotaxane formation between CBPQT4+ and biotin-functionalised guests.
The content of this RSS Feed (c) The Royal Society of Chemistry

Ylide mediated carbonyl homologations for the preparation of isatin derivatives

6 January, 2014 - 10:54

Org. Biomol. Chem., 2014, 12,406-409
DOI: 10.1039/C3OB42024H, CommunicationChristina T. Lollar, Katherine M. Krenek, Kevin J. Bruemmer, Alexander R. Lippert
An exceptionally mild method for the preparation of isatin derivatives has been developed using a sulfur ylide mediated carbonyl homologation sequence starting from anthranilic acid precursors.
The content of this RSS Feed (c) The Royal Society of Chemistry

C-H functionalization directed by transformable nitrogen heterocycles: synthesis of ortho-oxygenated arylnaphthalenes from arylphthalazines

6 January, 2014 - 10:54

Org. Biomol. Chem., 2014, 12,410-413
DOI: 10.1039/C3OB42255K, CommunicationShiva K. Rastogi, Derek C. Medellin, Alexander Kornienko
ortho-Oxygenated arylnaphthalenes were successfully synthesized from arylphthalazines by a new C-H oxidation reaction followed by transannulation using an Inverse Electron Demand Diels-Alder process.
The content of this RSS Feed (c) The Royal Society of Chemistry

Self-recovering stimuli-responsive macrocycle-equipped supramolecular ionogels with unusual mechanical properties

6 January, 2014 - 10:54

Org. Biomol. Chem., 2014, 12,503-510
DOI: 10.1039/C3OB41523F, PaperZhenhui Qi, Nora L. Traulsen, Paula Malo de Molina, Christoph Schlaich, Michael Gradzielski, Christoph A. Schalley
A chiral, crown-ether-functionalized bisurea gelator forms supramolecular gels in ionic liquids.
The content of this RSS Feed (c) The Royal Society of Chemistry

Et4NI-catalyzed amidation of aldehydes and alcohols with ammonium salts

6 January, 2014 - 10:54

Org. Biomol. Chem., 2014, 12,414-417
DOI: 10.1039/C3OB42037J, CommunicationGao Wang, Qing-Ying Yu, Shan-Yong Chen, Xiao-Qi Yu
An efficient Et4NI-catalyzed oxidative amidation of aldehydes or alcohols with ammonium salts.
The content of this RSS Feed (c) The Royal Society of Chemistry

[2n2[small pi] + 2n2[small pi]] Cycloadditions: an alternative to forbidden [4[small pi] + 4[small pi]] processes. The case of nitrone dimerization

6 January, 2014 - 10:54

Org. Biomol. Chem., 2014, 12,517-525
DOI: 10.1039/C3OB42014K, PaperDavid Roca-Lopez, Tomas Tejero, Pierluigi Caramella, Pedro Merino
The dimerization of nitrones is a concerted pseudopericyclic process.
The content of this RSS Feed (c) The Royal Society of Chemistry

Discovery of novel FabF ligands inspired by platensimycin by integrating structure-based design with diversity-oriented synthetic accessibility

6 January, 2014 - 10:54

Org. Biomol. Chem., 2014, 12,486-494
DOI: 10.1039/C3OB41975D, PaperMartin Fisher, Ramkrishna Basak, Arnout P. Kalverda, Colin W. G. Fishwick, W. Bruce Turnbull, Adam Nelson
A novel integrated approach for discovering bioactive small molecules is described.
The content of this RSS Feed (c) The Royal Society of Chemistry

WebElements: the periodic table on the WWW [http://www.webelements.com/]

Copyright 1993-2011 Mark Winter [The University of Sheffield and WebElements Ltd, UK]. All rights reserved.