Org. and Biomol. Chem.

Syndicate content RSC - Org. Biomol. Chem. latest articles
RSC - Org. Biomol. Chem. latest articles
Updated: 1 day 5 hours ago

Stereoelectronic effects: a simple yet powerful tool to manipulate anion affinity

7 January, 2015 - 03:17

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02470B, PaperMasoud Samet, Alireza Fattahi, Steven R. Kass
Stereoelectronic effects on anion binding were examined, IR spectroscopy was used to probe structures, and a well aligned non-interacting group can be more significant than a hydrogen bond donor.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Phosphate modulates receptor sulfotyrosine recognition by the chemokine monocyte chemoattractant protein-1 (MCP-1/CCL2)

7 January, 2015 - 03:17

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02262A, PaperJustin P. Ludeman, Mahdieh Nazari-Robati, Brendan L. Wilkinson, Cheng Huang, Richard J. Payne, Martin J. Stone
Fluorescence anisotropy shows that the physiological buffer phosphate competes with a chemokine receptor sulfopeptide for binding to a cognate chemokine.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

In situ intramolecular catalytic 1,2-addition of allenoates to cyclic ketones towards polycyclic allenoates

7 January, 2015 - 03:17

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02451F, PaperClement F. Heinrich, Michel Miesch, Laurence Miesch
Sequential deprotonation, isomerization of 3-alkynoates and subsequent 1,2-addition led to bicyclic allenoate in the presence of a catalytic amount of Cs2CO3.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

[small beta]-Ketothioamides: efficient reagents in the synthesis of heterocycles

7 January, 2015 - 03:17

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02024C, Review ArticleWei-Si Guo, Li-Rong Wen, Ming Li
[small beta]-Ketothioamides (KTAs) are versatile building blocks for the rapid construction of various heterocyclic compounds.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Synthesis and physico-chemical properties of the first water soluble Cu(II)@hemicryptophane complex

7 January, 2015 - 03:17

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02085E, PaperAline Schmitt, Solene Collin, Christophe Bucher, Vincent Maurel, Jean-Pierre Dutasta, Alexandre Martinez
A water-soluble metallo-enzyme model featuring a copper(II) site encaged in a closed-shell cavity of a hemicryptophane has been synthesized and studied.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Chemoselective efficient synthesis of functionalized [small beta]-oxonitriles through cyanomethylation of Weinreb amides

7 January, 2015 - 03:17

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02398F, CommunicationAshenafi Damtew Mamuye, Laura Castoldi, Ugo Azzena, Wolfgang Holzer, Vittorio Pace
Homologation of Weinreb amides with cyanomethyllithium: a new route to [small beta]-oxonitriles.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Tandem Catalytic Oxidative Deacetylation of Acetoacetic Esters and Hetero Aromatic Cyclizations

7 January, 2015 - 03:17
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB02441A, PaperYeming Ju, Di Miao, Ruiyang Yu, Sangho Koo
One pot syntheses of furan, thiophene, and pyrrole were accomplished by oxidative deacetylation using Mn(III)/Co(II) catalysts and Paal-Knorr reaction from 1,5-dicarbonyl compounds, which are prepared from the conjugate addition of...
The content of this RSS Feed (c) The Royal Society of Chemistry

Copper-Catalyzed Oxidative Alkenylation of Thioethers via Csp3-H Functionalization

7 January, 2015 - 03:17
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB02564D, CommunicationHao Cao, Dong Liu, Chao Liu, Xinquan Hu, Aiwen Lei
A novel copper-catalyzed oxidative alkenylation of thioethers via Csp3-H functionalization to construct allylic thioethers was first demonstrated. Different 1,1-disubstituted olefins could cross-couple with thioethers to generate the corresponding alkenylation products...
The content of this RSS Feed (c) The Royal Society of Chemistry

Solvent- and Phase-Controlled Photochirogenesis. Enantiodifferentiating Photoisomerization of (Z)-Cyclooctene Sensitized by Cyclic Nigerosylnigerose-Based Nanosponges Crosslinked by Pyromellitate

7 January, 2015 - 03:17
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB02390K, PaperXueqin Wei, Wenting Liang, Wanhua Wu, Cheng Yang, fabrizio caldera, Francesco Trotta, Andrea Mele, Tomoyuki Nishimoto, Yoshihisa Inoue
Cyclic nigerosylnigerose (CNN), a saucer-shaped cyclic tetrasaccharide with a shallow concave, was reacted with pyromellitic dianhydride in 1:2 and 1:4 ratios to give two CNN-based polymers of different degrees of...
The content of this RSS Feed (c) The Royal Society of Chemistry

1 H chemical shift differences of Prelog-Djerassi lactone derivatives: DFT and NMR conformational studies

7 January, 2015 - 03:17

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02446J, PaperTulio J. Aimola, Dimas J. P. Lima, Luiz C. Dias, Claudio F. Tormena, Marco A. B. Ferreira
This work reports an experimental and theoretical study of the conformational preferences of several Prelog-Djerassi lactone derivatives, to elucidate the 1H NMR chemical shift differences in the lactonic core that are associated with the relative stereochemistry of these derivatives.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Synthesis of enantiopure glycidol derivatives via a one-pot two-step enzymatic cascade

5 January, 2015 - 02:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02186J, PaperYu-Chang Liu, Yan Liu, Zhong-Liu Wu
An enzymatic cascade reaction employing an S-specific ketoreductase and a styrene monooxygenase to synthesize enantiopure glycidol derivatives is described.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Rapid detection of hydrazine in a naphthol-fused chromenyl loop and its effectiveness in human lung cancer cells: tuning remarkable selectivity via the reaction altered pathway supported by theoretical studies

5 January, 2015 - 02:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB01842G, PaperShyamaprosad Goswami, Avijit Kumar Das, Urmila Saha, Sibaprasad Maity, Kalyani Khanra, Nandan Bhattacharyya
A new chemosensor (NAC) is reported for fast and selective detection of N2H4 in a novel way.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Metal-free C-H amination of unactivated hydrocarbons with sulfonylimino-[small lambda]3-bromanes generated in situ from (diacetoxybromo)benzene

5 January, 2015 - 02:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02160F, PaperKazunori Miyamoto, Taiga Ota, Md. Mahbubul Hoque, Masahito Ochiai
A simple method for direct metal-free C-H amination of unactivated hydrocarbons using easy-handling diacetoxy-[small lambda]3-bromane and triflylamide or sulfamate esters was developed.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Tuning Viscoelastic Properties of Supramolecular Peptide Gels via Dynamic Covalent Crosslinking

5 January, 2015 - 02:54
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB02217C, CommunicationAref Khalily, Melis Goktas, Mustafa O. Guler
Dynamic covalent crosslinking approach is used to crosslink supramolecular peptide gels. This novel approach facilitates tuning viscoelastic properties of the gel and enhances mechanical stability (storage modulus exceeding 105 Pa)...
The content of this RSS Feed (c) The Royal Society of Chemistry

Phototriggerable peptidomimetics for the inhibition of Mycobacterium turberculosis ribonucleotide reductase by targeting protein-protein binding

5 January, 2015 - 02:54
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB01926A, PaperChristoffer Karlsson, Magnus Blom, Miranda Johansson, Anna M Jansson, Enzo Scifo, Anders Karlen, Thavendran Govender, Adolf Gogoll
Incorporation of an artificial amino acid 2 with a stilbene chromophore into peptidomimetics with three to nine amino acids yields phototriggerable candidates for inhibition of the binding between the R1...
The content of this RSS Feed (c) The Royal Society of Chemistry

Rapid and scalable assembly of firefly luciferase substrates

5 January, 2015 - 02:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02529F, PaperDavid C. McCutcheon, William B. Porterfield, Jennifer A. Prescher
Improved access to luciferins will bolster bioluminescence imaging applications.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Regulating the cytoprotective response in cancer cells using simultaneous inhibition of Hsp90 and Hsp70

5 January, 2015 - 02:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02531H, PaperY. Wang, S. R. McAlpine
Both heat shock protein 90 and 70 (Hsp90, Hsp70) are cytoprotective proteins that regulate cell function and faciliate cell growth by stabilizing and folding proteins.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Synthesis of novel polyhydroxylated pyrrolidine-triazole/-isoxazole hybrid molecules

5 January, 2015 - 02:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB01934B, PaperCheng-Kun Lin, Li-Wei Cheng, Huang-Yi Li, Wen-Yi Yun, Wei-Chieh Cheng
A straightforward synthesis of novel, 2-heterocyclyl polyhydroxylated pyrrolidines is described.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

A Sc(OTf)3-catalyzed cascade reaction of o-aminoacetophenone with methanamine: construction of dibenzo[b,h][1,6]naphthyridine derivatives

5 January, 2015 - 02:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02220C, PaperDan Mao, Jun Tang, Wenbo Wang, Xin Liu, Shengying Wu, Jianjun Yu, Limin Wang
A Sc(OTf)3-catalyzed and air-mediated cascade reaction was discovered as an efficient approach to the novel fluorescent fused-four-ring dibenzo[b,h][1,6]naphthyridine derivatives.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Transition metal catalyzed meta-C-H functionalization of aromatic compounds

5 January, 2015 - 02:54

Org. Biomol. Chem., 2015, Advance Article
DOI: 10.1039/C4OB02171A, Review ArticleJiong Yang
This review summarizes synthetic methods for directing group guided, transition metal catalyzed meta-C-H functionalization of aromatic compounds.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

WebElements: the periodic table on the WWW [http://www.webelements.com/]

Copyright 1993-2011 Mark Winter [The University of Sheffield and WebElements Ltd, UK]. All rights reserved.