Royal Society of Chemistry

"AND" luminescent "reactive" molecular logic gates: a gateway to multi-analyte bioimaging and biosensing

Org. and Biomol. Chem. - 7 December, 2014 - 20:17
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB02076F, Review ArticleAnthony ROMIEU
This review outlines examples that illustrate a recent and highly innovative concept in the field of (bio)molecular sensing, namely the simultaneous multi-analyte detection using "reactive" luminescent probes that are able...
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Preparation of cycloheptane ring by nucleophilic cyclopropanation of 1,2-diketones with bis(iodozincio)methane

Org. and Biomol. Chem. - 7 December, 2014 - 20:17

Org. Biomol. Chem., 2015, 13,241-247
DOI: 10.1039/C4OB01474J, PaperRyosuke Haraguchi, Yoshiaki Takada, Seijiro Matsubara
The nucleophlic cyclopropanation of hexa-1,5-diene-3,4-diones with bis(iodozincio)methane afforded the Zn alkoxides of cyclohepta-2,7-diene-1,2-diols stereospecifically via Zn alkoxides of cis-dialkenylcyclopropane-1,2-diols.
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6-Substituted 1,2-benzoxathiine-2,2-dioxides are isoform-selective inhibitors of human carbonic anhydrases IX, XII and VA

Org. and Biomol. Chem. - 7 December, 2014 - 20:17

Org. Biomol. Chem., 2015, 13,77-80
DOI: 10.1039/C4OB02155J, CommunicationMuhammet Tanc, Fabrizio Carta, Andrea Scozzafava, Claudiu T. Supuran
A series of 6-substituted 2-benzoxathiine-2,2-dioxides were synthesized starting from 2,5-dihydroxybenzaldehyde, and then screened in vitro for their inhibition properties against five human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms.
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Development of a novel fluorescence probe capable of assessing the cytoplasmic entry of siderophore-based conjugates

Org. and Biomol. Chem. - 7 December, 2014 - 20:17

Org. Biomol. Chem., 2015, 13,73-76
DOI: 10.1039/C4OB01810A, CommunicationHyeon Seok Kim, Woon Young Song, Hak Joong Kim
A novel fluorescence probe capable of assessing the cytoplasmic entry of siderophore-based conjugates was synthesized and evaluated by photochemical characterization and cell-based assays.
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Systematic methodology for the development of biocatalytic hydrogen-borrowing cascades: application to the synthesis of chiral [small alpha]-substituted carboxylic acids from [small alpha]-substituted [small alpha],[small beta]-unsaturated aldehydes

Org. and Biomol. Chem. - 7 December, 2014 - 20:17

Org. Biomol. Chem., 2015, 13,223-233
DOI: 10.1039/C4OB02282C, PaperTanja Knaus, Francesco G. Mutti, Luke D. Humphreys, Nicholas J. Turner, Nigel S. Scrutton
The development of hydrogen-borrowing biocatalytic cascades is presented and applied to the synthesis of diverse [small alpha]-chiral substituted carboxylic acids.
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The rapid synthesis of oxazolines and their heterogeneous oxidation to oxazoles under flow conditions

Org. and Biomol. Chem. - 7 December, 2014 - 20:17

Org. Biomol. Chem., 2015, 13,207-214
DOI: 10.1039/C4OB02105C, PaperSteffen Glockner, Duc N. Tran, Richard J. Ingham, Sabine Fenner, Zoe E. Wilson, Claudio Battilocchio, Steven V. Ley
A flow process to access oxazolines and oxazoles via a rapid and practical protocol is described.
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Synthesis of maculalactone A and derivatives for environmental fate tracking studies

Org. and Biomol. Chem. - 7 December, 2014 - 20:17

Org. Biomol. Chem., 2015, 13,199-206
DOI: 10.1039/C4OB02042A, PaperOpen Access Open Access Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Samuel L. Bader, Michael U. Luescher, Karl Gademann
Labelled probes of the antifouling natural product, maculalactone A, allow for distribution studies in Artemia salina.
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Biosynthesis of 8-hydroxyquinoline-2-carboxylic acid, an iron chelator from the gut of the lepidopteran Spodoptera littoralis

Org. and Biomol. Chem. - 7 December, 2014 - 20:17

Org. Biomol. Chem., 2015, 13,178-184
DOI: 10.1039/C4OB01857E, PaperJelena Pesek, Jiri Svoboda, Martina Sattler, Stefan Bartram, Wilhelm Boland
8-HQA is generated in the gut of Noctuid larvae from tryptophan as an iron chelator to control the gut microbiome.
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Stereoselective synthesis of 1,2-diamine containing indolines by a conjugate addition nitro-mannich reaction

Org. and Biomol. Chem. - 7 December, 2014 - 20:17

Org. Biomol. Chem., 2015, 13,170-177
DOI: 10.1039/C4OB01793E, PaperOpen Access Open Access Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.James C. Anderson, Ian B. Campbell, Sebastien Campos, Jonathan Shannon, Derek A. Tocher
The sequential use of the conjugate addition nitro-Mannich reaction, nitro reduction and then Pd-catalyzed intramolecular cyclisation allows the concise, stereodivergent synthesis of complex indolines.
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The stability of nitrogen-centered radicals

Org. and Biomol. Chem. - 7 December, 2014 - 20:17

Org. Biomol. Chem., 2015, 13,157-169
DOI: 10.1039/C4OB01656D, PaperJohnny Hioe, Davor Sakic, Valerije Vrcek, Hendrik Zipse
Radical stabilization energies (RSEs) for a large variety of aminyl and protonated amine radical cations have been calculated using high-level composite procedures.
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Functional importance of the sugar moiety of jasmonic acid glucoside for bioactivity and target affinity

Org. and Biomol. Chem. - 7 December, 2014 - 20:17

Org. Biomol. Chem., 2015, 13,55-58
DOI: 10.1039/C4OB02106A, CommunicationMinoru Ueda, Gangqiang Yang, Yuuki Nukadzuka, Yasuhiro Ishimaru, Satoru Tamura, Yoshiyuki Manabe
Importance of the D-glycopyranoside structure for the bioactivity and target affinity of jasmonic acid glucoside.
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Design and synthesis of potent hydroxamate inhibitors with increased selectivity within the gelatinase family

Org. and Biomol. Chem. - 7 December, 2014 - 20:17

Org. Biomol. Chem., 2015, 13,142-156
DOI: 10.1039/C4OB01516A, PaperJose Maria Zapico, Anna Puckowska, Kamila Filipiak, Claire Coderch, Beatriz de Pascual-Teresa, Ana Ramos
Triazole-based inhibitors with high potency and selectivity for MMP-2 were obtained through a click chemistry approach.
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FD 178: Optical forces in nanoplasmonic systems: How do they work, what can they be useful for?

Faraday Disc. - 7 December, 2014 - 17:54
Faraday Discuss., 2014, Accepted Manuscript
DOI: 10.1039/C4FD00224E, PaperOlivier Martin, T.V. Raziman, R.I. Wolke
In this article, we share our vision for a future nanofactory, where plasmonic trapping is used to control the different manufacturing steps associated with the transformation of initial nanostructures to...
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FD 177:Resolution Enhancement Through Microscopic Spatiotemporal Control

Faraday Disc. - 7 December, 2014 - 17:54
Faraday Discuss., 2014, Accepted Manuscript
DOI: 10.1039/C4FD00177J, PaperDebabrata Goswami, Dhiman Das, Soumendra Nath Bandyopadhyay
Operating at biologically benign conditions, multi-photon fluorescence imaging microscopy has benefitted immensely from recent developments in microscopic resolution enhancement. Fluorescence microscopy continues to be the best choice for experiments on...
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FD 178: Critical importance of gap modes between metal nanoparticles and metal substrates in surface enhanced Raman scattering

Faraday Disc. - 7 December, 2014 - 17:54
Faraday Discuss., 2014, Accepted Manuscript
DOI: 10.1039/C4FD00188E, PaperMasayuki Futamata
For efficient utilization of surface plasmons in surface enhanced Raman scattering (SERS), we investigated gap modes in flocculates of metal nanoparticles (MNPs), and between MNPs and metal substrates under an...
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FD 177:Vibrational Dynamics of the CO Stretching of 9-Fluorenone Studied by Visible-pump and Infrared-probe Spectroscopy

Faraday Disc. - 7 December, 2014 - 17:54
Faraday Discuss., 2014, Accepted Manuscript
DOI: 10.1039/C4FD00169A, PaperYuki Fukui, Kaoru Ohta, Keisuke Tominaga
We studied effects of hydrogen bond on the vibrational structures and the vibrational dynamics of the CO stretching mode of 9-fluorenone (FL) in the electronically excited state in aprotic and...
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Bridging silicon nanoparticles and thermoelectrics: phenylacetylene functionalization

Faraday Disc. - 7 December, 2014 - 17:54
Faraday Discuss., 2014, Advance Article
DOI: 10.1039/C4FD00109E, PaperShane P. Ashby, Jason A. Thomas, Jorge Garcia-Canadas, Gao Min, Jack Corps, Anthony V. Powell, Hualong Xu, Wei Shen, Yimin Chao
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Application of twin screw extrusion to the manufacture of cocrystals: scale-up of AMG 517-sorbic acid cocrystal production

Faraday Disc. - 7 December, 2014 - 17:54
Faraday Discuss., 2014, 170,235-249
DOI: 10.1039/C3FD00153A, PaperDominick Daurio, Karthik Nagapudi, Lan Li, Peter Quan, Fernando-Alvarez Nunez
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Is the equilibrium composition of mechanochemical reactions predictable using computational chemistry?

Faraday Disc. - 7 December, 2014 - 17:54
Faraday Discuss., 2014, 170,41-57
DOI: 10.1039/C3FD00162H, PaperOpen Access Open Access Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Peter J. Bygrave, David H. Case, Graeme M. Day
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Triboelectricity in insulating polymers: evidence for a mechanochemical mechanism

Faraday Disc. - 7 December, 2014 - 17:54
Faraday Discuss., 2014, 170,369-383
DOI: 10.1039/C3FD00118K, PaperLia Beraldo da Silveira Balestrin, Douglas Del Duque, Douglas Soares da Silva, Fernando Galembeck
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